STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIMK1LIM domain kinase 1. (593 aa)    
Predicted Functional Partners:
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.987
ENSANAP00000026737
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.987
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.969
BMPR2
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
0.935
LOC105719430
ADF-H domain-containing protein.
   
 0.923
LOC105709929
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.923
LIMK2
LIM domain kinase 2.
  
 
 
0.913
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
0.905
PAK1
Non-specific serine/threonine protein kinase.
    
0.903
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
0.903
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.