close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA94104.1Ferredoxin--NADP(+) reductase; In the C-terminal sectio; belongs to the ferredoxin-- NADP reductase family; Contains 2 4Fe-4S ferredoxin-type domains; KEGG: nfa:nfa25880 ferredoxin--NADP+ reductase. (555 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase (NADPH); Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules; Belongs to the glutamate synthase family; Contains 1 glutamine amidotransferase type-2 domain; KEGG: nfa:nfa960 glutamate synthase (NADPH/NADH) large chain.
  
 
 0.998
korA
2-oxoglutarate synthase; Component of KG oxidoreductase (KOR) that catalyzes the CoA-dependent oxidative decarboxylation of 2-oxoglutarate (alpha- ketoglutarate, KG) to succinyl-CoA. Methyl viologen can act as electron acceptor in vitr; the physiologic electron acceptor is unknown. Is involved in the alternative TCA pathway that functions concurrently with fatty acid beta-oxidation. Since a growing body of evidence indicates that lipids (for example cholesterol and fatty acids) are a predominant growth substrate for M. tuberculosis during infection, flux through KOR likely represents a [...]
  
  
 0.922
APB01081.1
KEGG: myv:G155_25945 indolepyruvate ferredoxin oxidoreductase.
  
  
 0.800
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.796
APA96164.1
This is an electron transfer partner for desA3; Contains 1 2Fe-2S ferredoxin-type domain; Contains 1 FAD-binding FR-type domain; KEGG: mbo:Mb3259c null; Oxidoreductases.
   
 0.759
APA97029.1
Vanillate monooxygenase; Belongs to the PDR/VanB family; Contains 1 2Fe-2S ferredoxin-type domain; Contains 1 FAD-binding FR-type domain; KEGG: eae:EAE_02340 vanillate O-demethylase ferredoxin subunit.
   
 0.759
APA99357.1
Vanillate monooxygenase; Belongs to the PDR/VanB family; Contains 1 2Fe-2S ferredoxin-type domain; Contains 1 FAD-binding FR-type domain; KEGG: ron:TE10_23180 vanillate O-demethylase ferredoxin subunit.
   
 0.759
APB00810.1
3-ketosteroid 9-alpha-monooxygenase; Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta-cleavage (By similarity); Contains 1 2Fe-2S ferredoxin-type domain; Contains 1 FAD-binding FR-type domain; KEGG: myv:G155_04260 3-ketosteroid 9alpha-monooxygenase subunit B.
   
 0.759
APB01030.1
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the cell from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower th [...]
   
 0.759
APB01851.1
3-ketosteroid 9-alpha-monooxygenase; Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta-cleavage (By similarity); Contains 1 2Fe-2S ferredoxin-type domain; Contains 1 FAD-binding FR-type domain; KEGG: nfa:nfa50680 3-ketosteroid 9alpha-monooxygenase subunit B.
   
 0.759
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.