| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94473.1 | APA94474.1 | NS506_00390 | NS506_00391 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | 0.913 |
| APA94473.1 | APA94475.1 | NS506_00390 | NS506_00392 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | Hypothetical protein. | 0.915 |
| APA94473.1 | APA94477.1 | NS506_00390 | NS506_00394 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | Hypothetical protein. | 0.734 |
| APA94473.1 | nth | NS506_00390 | NS506_00393 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.886 |
| APA94474.1 | APA94473.1 | NS506_00391 | NS506_00390 | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | 0.913 |
| APA94474.1 | APA94475.1 | NS506_00391 | NS506_00392 | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | Hypothetical protein. | 0.967 |
| APA94474.1 | APA94477.1 | NS506_00391 | NS506_00394 | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | Hypothetical protein. | 0.685 |
| APA94474.1 | nth | NS506_00391 | NS506_00393 | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.875 |
| APA94475.1 | APA94473.1 | NS506_00392 | NS506_00390 | Hypothetical protein. | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | 0.915 |
| APA94475.1 | APA94474.1 | NS506_00392 | NS506_00391 | Hypothetical protein. | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | 0.967 |
| APA94475.1 | APA94477.1 | NS506_00392 | NS506_00394 | Hypothetical protein. | Hypothetical protein. | 0.734 |
| APA94475.1 | APB00036.1 | NS506_00392 | NS506_05999 | Hypothetical protein. | Peroxiredoxin; Together with AhpD, DltA and Lpd constitutes an NADH- dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in detoxification of isoniazid (By similarity); Belongs to the AhpC/TSA family; Contains 1 thioredoxin domain; KEGG: mtu:Rv2428 peroxiredoxin (alkyl hydroperoxide reductase subunit C). | 0.885 |
| APA94475.1 | coxB | NS506_00392 | NS506_03264 | Hypothetical protein. | Cytochrome-c oxidase; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity); Belongs to the cytochrome c oxidase subunit 2 family; KEGG: nfa:nfa17080 cytochrome c oxidase subunit II. | 0.710 |
| APA94475.1 | dnaJ | NS506_00392 | NS506_01108 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.699 |
| APA94475.1 | msrA | NS506_00392 | NS506_00702 | Hypothetical protein. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.717 |
| APA94475.1 | msrA-2 | NS506_00392 | NS506_04884 | Hypothetical protein. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.717 |
| APA94475.1 | nth | NS506_00392 | NS506_00393 | Hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.883 |
| APA94475.1 | trxB | NS506_00392 | NS506_00286 | Hypothetical protein. | Thioredoxin-disulfide reductase; Probable member of the two-component regulatory system involved in the regulation of the hydrogenase activity. HoxA is probably phosphorylated by a sensory component (which could be HoxX) and then acts in conjunction with sigma-54 as a transcriptional activator. Contains 1 response regulatory domain; Contains 1 sigma-54 factor interaction domain; KEGG: ncy:NOCYR_5110 thioredoxin reductase (NADPH). | 0.762 |
| APA94477.1 | APA94473.1 | NS506_00394 | NS506_00390 | Hypothetical protein. | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | 0.734 |
| APA94477.1 | APA94474.1 | NS506_00394 | NS506_00391 | Hypothetical protein. | Putative nudix hydrolase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily; Contains 1 nudix hydrolase domain; KEGG: spu:580764 nudix motif 8; In phosphorus-containing anhydrides. | 0.685 |
