| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94498.1 | APA94499.1 | NS506_00416 | NS506_00417 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Hypothetical protein. | 0.841 |
| APA94498.1 | APA94500.1 | NS506_00416 | NS506_00418 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Hypothetical protein. | 0.841 |
| APA94498.1 | APA94501.1 | NS506_00416 | NS506_00419 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | KEGG: mah:MEALZ_0770 sterol 14-demethylase. | 0.839 |
| APA94498.1 | APA94502.1 | NS506_00416 | NS506_00420 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: ebi:EbC_10690 3-oxoacyl-(acyl-carrier protein) reductase. | 0.843 |
| APA94498.1 | APA94503.1 | NS506_00416 | NS506_00421 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Belongs to the cytochrome P450 family; KEGG: nfa:nfa25810 null; Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2). | 0.811 |
| APA94498.1 | APA94506.1 | NS506_00416 | NS506_00424 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | 3-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the 3-hydroxyisobutyrate dehydrogenase family; KEGG: xcv:XCV0331 null; With NAD(+) or NADP(+) as acceptor. | 0.447 |
| APA94498.1 | APA94507.1 | NS506_00416 | NS506_00425 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | KEGG: req:REQ_13740 4-carboxymuconolactone decarboxylase. | 0.426 |
| APA94498.1 | APA94513.1 | NS506_00416 | NS506_00431 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Putative HTH-type transcriptional regulator; Contains 1 HTH tetR-type DNA-binding domain. | 0.440 |
| APA94498.1 | APA94514.1 | NS506_00416 | NS506_00432 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Sterol 14-alpha-demethylase; Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene- 3-beta-ol (By similarity); Belongs to the cytochrome P450 family; KEGG: nfa:nfa25890 sterol 14-demethylase. | 0.665 |
| APA94498.1 | budC | NS506_00416 | NS506_00423 | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | Ketoacyl reductase HetN; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: eli:ELI_09045 meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase; With NAD(+) or NADP(+) as acceptor. | 0.482 |
| APA94499.1 | APA94498.1 | NS506_00417 | NS506_00416 | Hypothetical protein. | Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...] | 0.841 |
| APA94499.1 | APA94500.1 | NS506_00417 | NS506_00418 | Hypothetical protein. | Hypothetical protein. | 0.971 |
| APA94499.1 | APA94501.1 | NS506_00417 | NS506_00419 | Hypothetical protein. | KEGG: mah:MEALZ_0770 sterol 14-demethylase. | 0.967 |
| APA94499.1 | APA94502.1 | NS506_00417 | NS506_00420 | Hypothetical protein. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: ebi:EbC_10690 3-oxoacyl-(acyl-carrier protein) reductase. | 0.969 |
| APA94499.1 | APA94503.1 | NS506_00417 | NS506_00421 | Hypothetical protein. | Belongs to the cytochrome P450 family; KEGG: nfa:nfa25810 null; Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2). | 0.857 |
| APA94499.1 | APA94506.1 | NS506_00417 | NS506_00424 | Hypothetical protein. | 3-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the 3-hydroxyisobutyrate dehydrogenase family; KEGG: xcv:XCV0331 null; With NAD(+) or NADP(+) as acceptor. | 0.793 |
| APA94499.1 | APA94507.1 | NS506_00417 | NS506_00425 | Hypothetical protein. | KEGG: req:REQ_13740 4-carboxymuconolactone decarboxylase. | 0.819 |
| APA94499.1 | APA94513.1 | NS506_00417 | NS506_00431 | Hypothetical protein. | Putative HTH-type transcriptional regulator; Contains 1 HTH tetR-type DNA-binding domain. | 0.879 |
| APA94499.1 | APA94514.1 | NS506_00417 | NS506_00432 | Hypothetical protein. | Sterol 14-alpha-demethylase; Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene- 3-beta-ol (By similarity); Belongs to the cytochrome P450 family; KEGG: nfa:nfa25890 sterol 14-demethylase. | 0.874 |
| APA94499.1 | budC | NS506_00417 | NS506_00423 | Hypothetical protein. | Ketoacyl reductase HetN; May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating. Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: eli:ELI_09045 meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase; With NAD(+) or NADP(+) as acceptor. | 0.754 |
STRING v12.5 is now available!
