| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94602.1 | APA96442.1 | NS506_00520 | NS506_02376 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | 0.931 |
| APA94602.1 | APA96784.1 | NS506_00520 | NS506_02723 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains. | 0.851 |
| APA94602.1 | APA98059.1 | NS506_00520 | NS506_04011 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Chondramide synthase cmdD; Involved in the synthesis of chondramides. Activates R- beta-tyrosine and probably phenylalanine; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains. | 0.902 |
| APA94602.1 | APA99517.1 | NS506_00520 | NS506_05471 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Bacitracin synthase; Induces peptide synthesis, activates and incorporates five amino acids, forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 5 acyl carrier domains. | 0.866 |
| APA94602.1 | APA99518.1 | NS506_00520 | NS506_05472 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Aspartate racemase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 4 acyl carrier domains; KEGG: rha:RHA1_ro06664 aspartate racemase. | 0.853 |
| APA94602.1 | APB00106.1 | NS506_00520 | NS506_06069 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Long-chain-fatty-acid--AMP ligase FadD32; Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase (PKS) for further chain extension; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.973 |
| APA94602.1 | APB00300.1 | NS506_00520 | NS506_06264 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | 6-methylsalicylic acid synthase; Contains 3 acyl carrier domains; KEGG: fre:Franean1_3611 6-methylsalicylic acid synthase. | 0.950 |
| APA94602.1 | APB01672.1 | NS506_00520 | NS506_07652 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Chondramide synthase cmdD; Involved in the synthesis of chondramides. Activates R- beta-tyrosine and probably phenylalanine; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: rop:ROP_04690 enterobactin synthetase component F; Nucleotidyltransferases. | 0.849 |
| APA94602.1 | APB01742.1 | NS506_00520 | NS506_07723 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | 2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase; Catalyzes the activation of 2-hydroxy-7-methoxy-5- methyl-1-naphthoate in the biosynthesis of the naphthoate moiety of the neocarzinostatin chromophore. Also catalyzes the activation of other 1-naphthoic acid analogs such as 2-hydroxy-5-methyl-1- naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate in vitro; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.856 |
| APA94602.1 | murI | NS506_00520 | NS506_04324 | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | Glutamate racemase; Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 4 acyl carrier domains; KEGG: rha:RHA1_ro05452 glutamate racemase. | 0.858 |
| APA96442.1 | APA94602.1 | NS506_02376 | NS506_00520 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Mycocerosic acid synthase; Catalyzes the elongation of N-fatty acyl-CoA with methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids; Contains 1 acyl carrier domain. | 0.931 |
| APA96442.1 | APA96784.1 | NS506_02376 | NS506_02723 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains. | 0.999 |
| APA96442.1 | APA98059.1 | NS506_02376 | NS506_04011 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Chondramide synthase cmdD; Involved in the synthesis of chondramides. Activates R- beta-tyrosine and probably phenylalanine; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains. | 0.951 |
| APA96442.1 | APA99517.1 | NS506_02376 | NS506_05471 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Bacitracin synthase; Induces peptide synthesis, activates and incorporates five amino acids, forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 5 acyl carrier domains. | 0.685 |
| APA96442.1 | APA99518.1 | NS506_02376 | NS506_05472 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Aspartate racemase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 4 acyl carrier domains; KEGG: rha:RHA1_ro06664 aspartate racemase. | 0.986 |
| APA96442.1 | APB00106.1 | NS506_02376 | NS506_06069 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Long-chain-fatty-acid--AMP ligase FadD32; Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase (PKS) for further chain extension; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
| APA96442.1 | APB00300.1 | NS506_02376 | NS506_06264 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | 6-methylsalicylic acid synthase; Contains 3 acyl carrier domains; KEGG: fre:Franean1_3611 6-methylsalicylic acid synthase. | 0.982 |
| APA96442.1 | APB01672.1 | NS506_02376 | NS506_07652 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Chondramide synthase cmdD; Involved in the synthesis of chondramides. Activates R- beta-tyrosine and probably phenylalanine; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: rop:ROP_04690 enterobactin synthetase component F; Nucleotidyltransferases. | 0.987 |
| APA96442.1 | APB01742.1 | NS506_02376 | NS506_07723 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | 2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase; Catalyzes the activation of 2-hydroxy-7-methoxy-5- methyl-1-naphthoate in the biosynthesis of the naphthoate moiety of the neocarzinostatin chromophore. Also catalyzes the activation of other 1-naphthoic acid analogs such as 2-hydroxy-5-methyl-1- naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate in vitro; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.986 |
| APA96442.1 | murI | NS506_02376 | NS506_04324 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Glutamate racemase; Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 4 acyl carrier domains; KEGG: rha:RHA1_ro05452 glutamate racemase. | 0.987 |
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