STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
lhgOL-2-hydroxyglutarate oxidase LhgO; Oxidizes L-2-hydroxyglutarate, probably to recover alpha-ketoglutarate mistakenly reduced by other enzymes or formed during growth on propionate; Belongs to the L2HGDH family; KEGG: pst:PSPTOA0036 L-2-hydroxyglutarate oxidase; With oxygen as acceptor. (397 aa)    
Predicted Functional Partners:
APA94652.1
Hypothetical protein.
       0.766
APA94654.1
Hypothetical protein.
       0.623
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.615
gltB
Glutamate synthase (NADPH); Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules; Belongs to the glutamate synthase family; Contains 1 glutamine amidotransferase type-2 domain; KEGG: nfa:nfa960 glutamate synthase (NADPH/NADH) large chain.
  
  
 0.447
gltA
Citrate (Si)-synthase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield (2S,3S)-2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl- CoA; Belongs to the citrate synthase family; KEGG: rpm:RSPPHO_02006 citrate synthase.
  
  
 0.412
APB01796.1
Belongs to the citrate synthase family; KEGG: rhb:NY08_2544 citrate synthase.
  
  
 0.412
APB01799.1
Belongs to the citrate synthase family; KEGG: nbr:O3I_003710 citrate synthase.
  
  
 0.412
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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