| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94459.1 | APA94462.1 | NS506_00376 | NS506_00379 | Hypothetical protein. | Uncharacterized protein; May play a role in septum formation. | 0.724 |
| APA94459.1 | APA94669.1 | NS506_00376 | NS506_00587 | Hypothetical protein. | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | 0.447 |
| APA94459.1 | APA95462.1 | NS506_00376 | NS506_01390 | Hypothetical protein. | UPF0678 fatty acid-binding protein-like protein; May play a role in the intracellular transport of hydrophobic ligands. | 0.425 |
| APA94459.1 | APB00673.1 | NS506_00376 | NS506_06642 | Hypothetical protein. | Hypothetical protein. | 0.696 |
| APA94462.1 | APA94459.1 | NS506_00379 | NS506_00376 | Uncharacterized protein; May play a role in septum formation. | Hypothetical protein. | 0.724 |
| APA94462.1 | APA94669.1 | NS506_00379 | NS506_00587 | Uncharacterized protein; May play a role in septum formation. | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | 0.442 |
| APA94462.1 | APB00673.1 | NS506_00379 | NS506_06642 | Uncharacterized protein; May play a role in septum formation. | Hypothetical protein. | 0.633 |
| APA94473.1 | APA94669.1 | NS506_00390 | NS506_00587 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | 0.451 |
| APA94473.1 | APB01213.1 | NS506_00390 | NS506_07191 | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | Uncharacterized protein; To M. tuberculosis Rv1312. | 0.462 |
| APA94669.1 | APA94459.1 | NS506_00587 | NS506_00376 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Hypothetical protein. | 0.447 |
| APA94669.1 | APA94462.1 | NS506_00587 | NS506_00379 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Uncharacterized protein; May play a role in septum formation. | 0.442 |
| APA94669.1 | APA94473.1 | NS506_00587 | NS506_00390 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Serine protease; Required for M. tuberculosis resistance to oxidative stress in addition to its role in resistance to acid, which is essential for virulence; Belongs to the peptidase S1C family; Contains 1 peptidase S1 domain. | 0.451 |
| APA94669.1 | APA94670.1 | NS506_00587 | NS506_00588 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family; Contains 1 ABC transmembrane type-1 domain. | 0.469 |
| APA94669.1 | APA94671.1 | NS506_00587 | NS506_00589 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Putative ABC transporter permease protein; Probably part of a binding-protein-dependent transport system PH1036/38/39. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily; Contains 1 ABC transmembrane type-1 domain. | 0.456 |
| APA94669.1 | APA95462.1 | NS506_00587 | NS506_01390 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | UPF0678 fatty acid-binding protein-like protein; May play a role in the intracellular transport of hydrophobic ligands. | 0.518 |
| APA94669.1 | APA95690.1 | NS506_00587 | NS506_01620 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Resuscitation-promoting factor Rpf2; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells; Belongs to the transglycosylase family. Rpf subfamily; Contains 1 G5 domain. | 0.462 |
| APA94669.1 | APB00673.1 | NS506_00587 | NS506_06642 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Hypothetical protein. | 0.564 |
| APA94669.1 | APB01213.1 | NS506_00587 | NS506_07191 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | Uncharacterized protein; To M. tuberculosis Rv1312. | 0.462 |
| APA94669.1 | arsA | NS506_00587 | NS506_00399 | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | KEGG: pbm:CL52_01750 arsenite-transporting ATPase. | 0.461 |
| APA94670.1 | APA94669.1 | NS506_00588 | NS506_00587 | Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family; Contains 1 ABC transmembrane type-1 domain. | L,D-transpeptidase; Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection; Contains 1 YkuD domain. | 0.469 |