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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA94862.1Diacylglycerol O-acyltransferase; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM [...] (347 aa)    
Predicted Functional Partners:
APA94871.1
Hypothetical protein.
 
     0.788
aftB
Terminal beta-(1->2)-arabinofuranosyltransferase; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids; Belongs to the AftB family; KEGG: ncy:NOCYR_0136 arabi [...]
 
     0.786
APA95947.1
May function as a peptidoglycan hydrolase with glycosidase activity. In vitro, displays esterase activity toward p-nitrophenyl esters of various acyl chain length (C4 to C16), with a preference for p-nitrophenyl butyrate (C4).
  
     0.752
aftC
Arabinofuranan 3-O-arabinosyltransferase; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the addition of arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C- 3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG; Belongs to the glycosyltransferase 87 family; KEGG: nfa:nfa37340 arabinofuranan 3-O-arabinosyltransferase.
  
     0.751
APA94666.1
Hypothetical protein.
 
     0.742
APA94270.1
Hypothetical protein.
  
     0.739
APA97128.1
Cutinase; KEGG: cter:A606_03065 cutinase.
  
     0.735
APB01112.1
Cutinase; May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; Contains 1 DAD (diaphanous autoregulatory) domain; KEGG: cter:A606_03065 cutinase.
  
     0.726
APA94757.1
Cutinase; KEGG: cter:A606_03065 cutinase.
  
     0.714
lpqB
Belongs to the LpqB lipoprotein family.
  
     0.709
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (46%) [HD]
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