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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
APA94886.1Decaprenylphospho-beta-D-erythro-pentofuranosid- 2-ulose 2-reductase; Dpre1 and DprE2 are involved in the epimerization of decaprenylphosphoryl-beta-D-ribofuranose (DPR) to decaprenylphosphoryl-beta-D-arabinofuranose (DPA), the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers. The reaction proceeds via the keto intermediate decaprenylphosphoryl-D-2-keto-erythro-pentofuranose (DPX). DprE2 catalyzes the NAD-dependent reduction at the C-2 of DPX to yield DPA; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: mtu:Rv3791 decaprenylpho [...] (253 aa)    
Predicted Functional Partners:
APA94887.1
Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase; Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX) (By similarity); Contains 1 FAD-binding PCMH-type domain; KEGG: asd:AS9A_0118 decaprenylphospho-beta-D-ribofuranose 2-oxidase.
 
  
 0.979
APA94888.1
Uncharacterized protein; Belongs to the GtrA family.
 
   
 0.930
APA97884.1
Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase; Dpre1 and DprE2 are involved in the epimerization of decaprenylphosphoryl-beta-D-ribofuranose (DPR) to decaprenylphosphoryl-beta-D-arabinofuranose (DPA), the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers. The reaction proceeds via the keto intermediate decaprenylphosphoryl-D-2-keto-erythro-pentofuranose (DPX). DprE1 catalyzes the FAD-dependent oxidation at the C-2 of DPR to yield DPX. It can also use farnesylphosphoryl-beta-D-ribofuranose (FPR) as substrate and 2,6-dichlorophenolindophenol (DCPI [...]
 
  
 0.912
aftA
Galactan 5-O-arabinofuranosyltransferase; Involved in cell wall arabinan biosynthesis. Catalyzes the addition of the first key arabinofuranosyl residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol to the galactan domain of the cell wall, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases (By similarity); Belongs to the glycosyltransferase 85 family; KEGG: nfa:nfa1950 galactan 5-O-arabinofuranosyltransferase.
 
   
 0.846
APA94860.1
Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase.
 
  
 0.822
APA97431.1
Putative arabinosyltransferase; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. Belongs to the emb family; KEGG: ncy:NOCYR_1889 arabinosyltransferase C; Pentosyltransferases.
 
   
 0.664
APA96839.1
Putative arabinosyltransferase B; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. Belongs to the emb family; KEGG: ncy:NOCYR_0151 arabinosyltransferase C; Pentosyltransferases.
 
   
 0.649
bcrC
Undecaprenyl-diphosphate phosphatase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Could be involved in the dephosphorylation of decaprenylphosphoryl-5-phosphoribose (DPPR) to decaprenyl-phospho-ribose (DPR) (By similarity); Belongs to the PA-phosphatase related phosphoesterase family; KEGG: mva:Mvan_5648 undecaprenyl-diphosphatase.
 
   
 0.648
embC
Putative arabinosyltransferase B; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. Belongs to the emb family; KEGG: nno:NONO_c01550 arabinosyltransferase C; Pentosyltransferases.
 
   
 0.643
embB
Putative arabinosyltransferase; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. Belongs to the emb family; KEGG: ncy:NOCYR_0148 arabinosyltransferase B; Pentosyltransferases.
 
   
 0.637
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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