STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA94957.1Hypothetical protein. (195 aa)    
Predicted Functional Partners:
APA94958.1
Putative HTH-type transcriptional regulator; Contains 1 HTH rrf2-type DNA-binding domain.
       0.660
APB00496.1
Nitrogen regulatory protein P-II; In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP, these events are reversed (By similarity); Be [...]
     
 0.532
APA99459.1
Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length; Contains 1 HTH tetR-type DNA-binding domain.
  
     0.509
APB01856.1
Hypothetical protein.
  
     0.496
APA99074.1
Hypothetical protein.
  
     0.489
APB00938.1
Putative HTH-type transcriptional regulator ArpR; Probable regulatory protein for the antibiotic efflux pump arpABC operon. May function as a repressor (By similarity); Contains 1 HTH tetR-type DNA-binding domain.
  
     0.472
APA96330.1
HTH-type transcriptional repressor AcnR; AcnR negatively controls the expression of the aconitase gene acn; Contains 1 HTH tetR-type DNA-binding domain.
  
     0.464
APA94956.1
Membrane protein YdfJ; Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily.
       0.461
APA94959.1
Putative ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily; Contains 1 ABC transmembrane type-1 domain; Contains 1 ABC transporter domain.
       0.455
APA94960.1
Putative ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. MsbA family; Contains 1 ABC transmembrane type-1 domain; Contains 1 ABC transporter domain.
       0.455
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.