| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94723.1 | APA95092.1 | NS506_00643 | NS506_01018 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | 0.957 |
| APA94723.1 | APA95754.1 | NS506_00643 | NS506_01685 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May play a role in pathogenicity, not only by hydrolyzing cAMP, but also by altering properties of the cell wall (By similarity); Belongs to the cAMP phosphodiesterase class-III family. | 0.906 |
| APA94723.1 | APA95886.1 | NS506_00643 | NS506_01818 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa48200 adenylate cyclase. | 0.962 |
| APA94723.1 | APA97573.1 | NS506_00643 | NS506_03521 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Belongs to the pyruvate kinase family; In the C-terminal sectio; belongs to the PEP- utilizing enzyme family; KEGG: cva:CVAR_1215 pyruvate kinase. | 0.911 |
| APA94723.1 | APA99205.1 | NS506_00643 | NS506_05159 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Belongs to the pyruvate kinase family; KEGG: mva:Mvan_0632 pyruvate kinase. | 0.911 |
| APA94723.1 | APA99209.1 | NS506_00643 | NS506_05163 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Hypothetical protein. | 0.904 |
| APA94723.1 | APA99634.1 | NS506_00643 | NS506_05588 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.904 |
| APA94723.1 | cpdA | NS506_00643 | NS506_05305 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
| APA94723.1 | cpdA-2 | NS506_00643 | NS506_07734 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
| APA94723.1 | ndk | NS506_00643 | NS506_06861 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.906 |
| APA95092.1 | APA94723.1 | NS506_01018 | NS506_00643 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase. | 0.957 |
| APA95092.1 | APA95754.1 | NS506_01018 | NS506_01685 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. May play a role in pathogenicity, not only by hydrolyzing cAMP, but also by altering properties of the cell wall (By similarity); Belongs to the cAMP phosphodiesterase class-III family. | 0.904 |
| APA95092.1 | APA95886.1 | NS506_01018 | NS506_01818 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa48200 adenylate cyclase. | 0.922 |
| APA95092.1 | APA97573.1 | NS506_01018 | NS506_03521 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Belongs to the pyruvate kinase family; In the C-terminal sectio; belongs to the PEP- utilizing enzyme family; KEGG: cva:CVAR_1215 pyruvate kinase. | 0.911 |
| APA95092.1 | APA99205.1 | NS506_01018 | NS506_05159 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Belongs to the pyruvate kinase family; KEGG: mva:Mvan_0632 pyruvate kinase. | 0.911 |
| APA95092.1 | APA99209.1 | NS506_01018 | NS506_05163 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Hypothetical protein. | 0.904 |
| APA95092.1 | APA99634.1 | NS506_01018 | NS506_05588 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.903 |
| APA95092.1 | cpdA | NS506_01018 | NS506_05305 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |
| APA95092.1 | cpdA-2 | NS506_01018 | NS506_07734 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |
| APA95092.1 | ndk | NS506_01018 | NS506_06861 | Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.906 |