close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaAValine--pyruvate transaminase; Involved in the biosynthesis of alanine; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: asd:AS9A_4094 alanine-synthesizing transaminase. (403 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family; KEGG: mgi:Mflv_5171 dihydroxy-acid dehydratase.
  
 
 0.922
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family; KEGG: myv:G155_10260 dihydroxy-acid dehydratase.
  
 
 0.922
APB01082.1
Valine dehydrogenase (NAD(+)); Catalyzes the reversible, NAD-dependent deamination of L-phenylalanine to phenyl pyruvate, ammonia and NADH; Belongs to the Glu/Leu/Phe/Val dehydrogenases family; KEGG: ncy:NOCYR_1282 valine dehydrogenase (NAD+).
  
 
 0.915
argJ
Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
 
 0.913
APA97299.1
Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family; KEGG: nno:NONO_c22830 branched-chain amino acid aminotransferase.
  
 
 0.911
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.909
APA99729.1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
  
 
 0.909
APA97150.1
Alanine dehydrogenase; May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer; Belongs to the AlaDH/PNT family; KEGG: mag:amb4487 alanine dehydrogenase.
     
 0.906
ald
NAD(P)(+) transhydrogenase (Re/Si-specific); May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer; Belongs to the AlaDH/PNT family; KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha.
     
 0.906
APB00164.1
Amino-acid N-acetyltransferase; Catalyzes the conversion of L-glutamate to alpha-N- acetyl-L-glutamate. L-glutamine is a significantly better substrate compared to L-glutamate; Belongs to the acetyltransferase family; Contains 1 N-acetyltransferase domain; KEGG: svi:Svir_25180 amino-acid N-acetyltransferase.
     
 0.904
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.