STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cutCCopper homeostasis protein cutC like protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (285 aa)    
Predicted Functional Partners:
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
 
   
 0.751
APA95617.1
Beta-N-acetylhexosaminidase; Active during metamorphosis to degrade chitin. Belongs to the glycosyl hydrolase 20 family; KEGG: cai:Caci_5654 hexosaminidase.
 
     0.691
APA98267.1
PTS system N-acetylglucosamine-specific EIICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport. Contains 1 PTS EIIA type-1 domain; Contains 1 PTS EIIB type-1 domain; Contains 1 PTS EIIC type-1 domain.
 
  
 0.597
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.587
APA98270.1
N-acetylglucosamine-6-phosphate deacetylase; Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate; Belongs to the NagA family; KEGG: rha:RHA1_ro01548 N-acetylglucosamine-6-phosphate deacetylase.
 
     0.531
APA95156.1
Has endoglucanase activity on carboxymethyl-cellulose (CMC), cellobiosidase activity on p-nitrophenyl-cellobioside (p- NPC), and partial hydrolytic activity on crystalline cellulose (Avicel). Belongs to the glycosyl hydrolase 5 (cellulase A) family; Contains 1 CBM2 (carbohydrate binding type-2) domain.
 
   
 0.519
nagA
N-acetylglucosamine-6-phosphate deacetylase; Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate; Belongs to the NagA family; KEGG: nbr:O3I_039375 N-acetylglucosamine-6-phosphate deacetylase.
 
     0.512
APA96400.1
Glucokinase; Belongs to the ROK (NagC/XylR) family; KEGG: nbr:O3I_039370 glucokinase.
   
 0.494
APA95158.1
Uncharacterized protein; Contains 2 4Fe-4S ferredoxin-type domains; KEGG: gfo:GFO_1637 null; Oxidoreductases.
       0.493
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
       0.472
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.