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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA95215.1Putative zinc metalloprotease Rip2; Belongs to the peptidase M50B family. (263 aa)    
Predicted Functional Partners:
APA95216.1
Hypothetical protein.
       0.764
ksgA
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
     
 0.470
ftsW
Putative lipid II flippase FtsW; Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity); Belongs to the SEDS family. FtsW subfamily.
 
   
 0.433
rseP
Zinc metalloprotease Rip1; A probable intramembrane site-2 protease (S2P). Cleaves PbpB (PBP3, FtsI; cleavage is inhibited by Wag31-PbpB interaction. Probably also cleaves anti-sigma factors RskA, RslA and RsmA (By similarity); Regulated intramembrane proteolysis (RIP) occurs when an extracytoplasmic signal (possibly oxidative stress) triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein (includes anti-sigma factors RskA, RslA, RsmA, and PbpB in M. tuberculosis) is first cut extracytoplasmicall [...]
 
   
 0.433
APA98349.1
Uncharacterized protein; In the N-terminal sectio; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.414
APA98728.1
Uncharacterized protein; In the N-terminal sectio; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.414
APA98387.1
Uncharacterized protein; ATP-binding; Cell wall; Nucleotide-binding; Secreted.
  
  
 0.400
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (50%) [HD]
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