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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA95250.1KEGG: msm:MSMEG_3780 adenylate cyclase. (356 aa)    
Predicted Functional Partners:
APA95249.1
Hypothetical protein.
   
   0.679
APA95865.1
Hypothetical protein.
 
 0.654
APA99217.1
Uncharacterized protein; Contains 1 PAC (PAS-associated C-terminal) domain; Contains 1 PAS (PER-ARNT-SIM) domain; Contains 1 PPM-type phosphatase domain; Contains 1 STAS domain; KEGG: mmc:Mmcs_0350 null; Phosphotransferases with a nitrogenous group as acceptor.
  
 
 0.645
APA95092.1
Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa54940 adenylate cyclase.
  
   
 0.643
glnL
Histidine kinase; NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of NtrC. In nitrogen limitation NtrB activates NtrC by phosphorylating it, while in nitrogen excess NtrC is dephosphorylated and consequently inactivated by NtrB. Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: apb:SAR116_0215 two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL.
  
 0.577
APA98140.1
Hypothetical protein.
   
 0.561
APA95886.1
Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; Contains 1 HAMP domain; KEGG: nfa:nfa48200 adenylate cyclase.
  
   
 0.552
APA94723.1
Belongs to the adenylyl cyclase class-3 family; Contains 1 guanylate cyclase domain; KEGG: nfa:nfa6840 adenylate cyclase.
  
   
 0.543
APA94478.1
Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA- bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Activates expression of whiB1; Contains 1 cyclic nucleotide-binding domain; Contains 1 HTH crp-type DNA-binding domain.
  
 0.520
APA98124.1
Hypothetical protein.
  
     0.512
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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