node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | NS506_06935 | NS506_01339 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | 0.997 |
purC | purE | NS506_06935 | NS506_07283 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.994 |
purC | purF | NS506_06935 | NS506_01374 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.933 |
purC | purH | NS506_06935 | NS506_01505 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Belongs to the PurH family; KEGG: eco:b4006 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.970 |
purC | purK | NS506_06935 | NS506_07284 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.945 |
purC | purL | NS506_06935 | NS506_01361 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.932 |
purC | purL-2 | NS506_06935 | NS506_01367 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.939 |
purC | purM | NS506_06935 | NS506_01380 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Belongs to the AIR synthase family; KEGG: ncy:NOCYR_0593 phosphoribosylformylglycinamidine cyclo-ligase. | 0.955 |
purC | purN | NS506_06935 | NS506_01504 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.963 |
purC | purQ | NS506_06935 | NS506_01362 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.933 |
purD | purC | NS506_01339 | NS506_06935 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family; KEGG: nfa:nfa13190 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.997 |
purD | purE | NS506_01339 | NS506_07283 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | NS506_01339 | NS506_01374 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
purD | purH | NS506_01339 | NS506_01505 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Belongs to the PurH family; KEGG: eco:b4006 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.989 |
purD | purK | NS506_01339 | NS506_07284 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.976 |
purD | purL | NS506_01339 | NS506_01361 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.952 |
purD | purL-2 | NS506_01339 | NS506_01367 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.987 |
purD | purM | NS506_01339 | NS506_01380 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Belongs to the AIR synthase family; KEGG: ncy:NOCYR_0593 phosphoribosylformylglycinamidine cyclo-ligase. | 0.999 |
purD | purN | NS506_01339 | NS506_01504 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | NS506_01339 | NS506_01362 | Phosphoribosylamine--glycine ligase; Belongs to the GARS family; Contains 1 ATP-grasp domain; KEGG: brh:RBRH_02487 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.979 |