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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aacSAcetoacetate--CoA ligase; Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2); Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: mva:Mvan_5298 acetoacetyl-CoA synthetase. (644 aa)    
Predicted Functional Partners:
fadJ
3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate; In the N-terminal sectio; belongs to the enoyl-CoA hydratase/isomerase family; In the C-terminal sectio; belongs to the 3- hydroxyacyl-CoA dehydrogenase family; KEGG: cter:A606_01190 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
  
 0.958
paaH
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; KEGG: nfa:nfa52290 3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.932
APA96352.1
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; KEGG: nfa:nfa38400 3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.932
APA97835.1
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; KEGG: pap:PSPA7_1552 3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.932
hmgL
Hydroxymethylglutaryl-CoA lyase; Involved in the catabolism of branched amino acids such as leucine; Belongs to the HMG-CoA lyase family; KEGG: msa:Mycsm_01812 hydroxymethylglutaryl-CoA lyase.
 
 
 0.931
APA98097.1
Hypothetical protein.
  
 
 0.923
APA98017.1
3-hydroxybutyrate dehydrogenase; Catalyzes the conversion of 5'-hydroxyaverantin to 5'- oxoaverantin in the aflatoxin biosynthesis pathway. 5'- oxoaverantin spontaneously forms averufin (AVF) by intramolecular ketalisation; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: aza:AZKH_2574 3-hydroxybutyrate dehydrogenase.
   
  0.903
APA98018.1
Acetoacetate--CoA ligase; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: nfa:nfa28650 acetoacetyl-CoA synthetase.
  
  
 
0.901
APA95499.1
KEGG: llo:LLO_3026 itaconyl-CoA hydratase.
  
  
 0.816
APA95498.1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, myristoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons. Belongs to the acyl-CoA dehydrogenase family; KEGG: msm:MSMEG_4715 null; With other acceptors.
  
  
 0.803
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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