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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobFKEGG: fau:Fraau_1604 precorrin-6A synthase. (249 aa)    
Predicted Functional Partners:
APA99090.1
Precorrin-6A reductase; Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y. Belongs to the precorrin-6x reductase family; KEGG: nno:NONO_c34230 precorrin-6A/cobalt-precorrin-6A reductase.
 
 
 0.997
cobM
Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5. Belongs to the precorrin methyltransferase family; KEGG: spoi:IMCC21906_00669 precorrin-4/cobalt-precorrin-4 C11-methyltransferase.
 
 
 0.995
cobL
Precorrin-6B C(5,15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-5 in cobalt-precorrin-7 to form cobalt-precorrin-8. Belongs to the precorrin methyltransferase family; KEGG: nfa:nfa31560 precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
  
 0.955
APA99083.1
Catalyzes the conversion of precorrin-8X to hydrogenobyrinate; Belongs to the CobH/CbiC family; KEGG: nfa:nfa31510 precorrin-8X/cobalt-precorrin-8 methylmutase.
 
  
 0.938
cobA
Uroporphyrinogen-III C-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A; Belongs to the precorrin methyltransferase family; KEGG: tol:TOL_1445 uroporphyrin-III C-methyltransferase.
 
  
0.841
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.832
cobN
Cobaltochelatase; Belongs to the Mg-chelatase subunit H family; KEGG: asd:AS9A_2046 cobaltochelatase CobN.
 
  
 0.799
cobS
Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.705
cobO
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids (By similarity); Belongs to the Cob(I)alamin adenosyltransferase family; KEGG: nfa:nfa40820 cob(I)alamin adenosyltransferase.
 
   
 0.690
APB00709.1
Putative S-adenosylmethionine-dependent methyltransferase; Belongs to the methyltransferase superfamily.
  
  
 0.610
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (46%) [HD]
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