close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruBThe phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity); Contains 1 PTS EIIA type-2 domain; Contains 1 PTS EIIB type-2 domain; Contains 1 PTS EIIC type-2 domain; KEGG: cpu:cpfrc_01238 PTS system, fructose-specific IIA component. (667 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase involved in the utilization of fructose as a sole carbon and energy source; Belongs to the carbohydrate kinase PfkB family; KEGG: mva:Mvan_0095 1-phosphofructokinase.
 
 
 0.999
APA95823.1
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). Belongs to the HPr family; Contains 1 HPr domain.
 
 
 0.998
APA97143.1
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIIB type-2 domain; Contains 1 PTS EIIC type-2 domain; KEGG: mcb:Mycch_0084 PTS system, fructose-specific IIA component.
 
 
0.997
APA98268.1
Phosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). Belongs to the HPr family; Contains 1 HPr domain.
 
 
 0.995
APA94569.1
Phosphotransferase subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaM serves as the phosphoryl donor. It is phosphorylated by HPr, then it donates its phosphoryl group to DhaL-ADP, which eventually transmits it to dihydroxyacetone. Belongs to the PEP-utilizing enzyme family; Contains 1 HPr domain; Contains 1 PTS EIIA type-4 domain.
 
  
 0.990
APA95820.1
Repressor of the glycerol-3-phosphate regulon; Contains 1 HTH deoR-type DNA-binding domain.
 
  
 0.990
lacC
Belongs to the carbohydrate kinase PfkB family. LacC subfamily; KEGG: bcr:BCAH187_A2110 tagatose 6-phosphate kinase.
 
  
 0.987
APA96378.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily; KEGG: vvu:VV2_0199 1-phosphofructokinase.
 
  
 0.987
APA98464.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily; KEGG: pgb:H744_2c2228 1-phosphofructokinase.
 
  
 0.981
ptsI
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.978
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.