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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA96082.1Long-chain-fatty-acid--CoA ligase; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: sth:STH3016 long-chain acyl-CoA synthetase. (411 aa)    
Predicted Functional Partners:
APA96452.1
Fatty acid synthase subunit beta; Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. Belongs to the fungal fatty acid synthetase subunit beta family; Contains 1 MaoC-like domain; KEGG: nno:NONO_c62310 fatty acid synthase, bacteria type; Transferring groups other than amino-acyl groups.
  
 
 0.922
mglL
Acylglycerol lipase; Belongs to the AB hydrolase superfamily; KEGG: msm:MSMEG_0220 acylglycerol lipase.
    
  0.800
APA97686.1
4-coumarate--CoA ligase-like; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: nno:NONO_c28910 fatty-acyl-CoA synthase; Acid--thiol ligases.
  
   
 0.763
menE
o-succinylbenzoate--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA). May be involved in the biosynthesis of menaquinone (By similarity); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily; KEGG: rop:ROP_16850 O-succinylbenzoic acid--CoA ligase.
  
     0.757
APA98091.1
2-succinylbenzoate--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily; KEGG: mav:MAV_5076 fatty-acyl-CoA synthase; Acid--thiol ligases.
  
     0.751
APA98240.1
Malonate--CoA ligase that catalyzes the formation of malonyl-CoA directly from malonate and CoA. May be required for the detoxification of malonate; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: mpa:MAP4048c fatty-acyl-CoA synthase; Acid--thiol ligases.
  
     0.747
APA96585.1
3-((3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl)propanoyl:CoA ligase; Involved in the catabolism of the rings C and D of cholesterol. Catalyzes the ATP-dependent CoA thioesterification of 3aalpha-H-4alpha(3'-propanoate)-7abeta-methylhexahydro-1, 5- indanedione (HIP); Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: nbr:O3I_034255 fatty-acyl-CoA synthase; Acid--thiol ligases.
  
   
 0.746
APA98371.1
Bacitracin synthase; Activates five amino acids, incorporates two D-amino acids, releases and cyclizes the mature bacitracin. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 5 acyl carrier domains.
 
 
 0.746
aliA
Long-chain-fatty-acid--CoA ligase; Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: aac:Aaci_2400 cyclohexanecarboxylate-CoA ligase; Acid--thiol ligases.
  
     0.746
APA98459.1
Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: pgb:H744_1c0425 acetyl-CoA [...]
 
 
 0.745
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (50%) [HD]
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