| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94122.1 | dkgA | NS506_00031 | NS506_02156 | Pyridoxine 4-dehydrogenase; Belongs to the aldo/keto reductase family; KEGG: bur:Bcep18194_B1236 pyridoxine 4-dehydrogenase. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.577 |
| APA96224.1 | APA96225.1 | NS506_02157 | NS506_02158 | Hypothetical protein. | KEGG: dpd:Deipe_0121 probable phosphoglycerate mutase. | 0.543 |
| APA96224.1 | dkgA | NS506_02157 | NS506_02156 | Hypothetical protein. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.773 |
| APA96225.1 | APA96224.1 | NS506_02158 | NS506_02157 | KEGG: dpd:Deipe_0121 probable phosphoglycerate mutase. | Hypothetical protein. | 0.543 |
| APA96225.1 | dkgA | NS506_02158 | NS506_02156 | KEGG: dpd:Deipe_0121 probable phosphoglycerate mutase. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.560 |
| APA98789.1 | dkgA | NS506_04743 | NS506_02156 | Aryl-alcohol dehydrogenase (NADP(+)); Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily; KEGG: bra:BRADO6605 aryl-alcohol dehydrogenase (NADP+). | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.706 |
| APB00029.1 | dkgA | NS506_05992 | NS506_02156 | Pyridoxine 4-dehydrogenase; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily; KEGG: bur:Bcep18194_B2855 pyridoxine 4-dehydrogenase. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.586 |
| APB00708.1 | dkgA | NS506_06677 | NS506_02156 | KEGG: aav:Aave_4523 superoxide dismutase, Cu-Zn family. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.630 |
| APB00708.1 | otsB | NS506_06677 | NS506_01225 | KEGG: aav:Aave_4523 superoxide dismutase, Cu-Zn family. | Trehalose-phosphatase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose. Does not hydrolyze maltose, isomaltose, sucrose, cellobiose, p-nitrophenyl-alpha-D- glucopyranoside, and methyl-alpha-D-glucopyranoside. Is also inactive on alpha,beta-trehalose, beta,beta-trehalose, alpha,alpha-trehalose-6,6'-dibehenate, trehalulose, nigerose, and trehalose dimycolate; Belongs to the glycosyl hydrolase 15 family; KEGG: mab:MAB_0578c trehalose 6-phosphate phosphatase. | 0.581 |
| dkgA | APA94122.1 | NS506_02156 | NS506_00031 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Pyridoxine 4-dehydrogenase; Belongs to the aldo/keto reductase family; KEGG: bur:Bcep18194_B1236 pyridoxine 4-dehydrogenase. | 0.577 |
| dkgA | APA96224.1 | NS506_02156 | NS506_02157 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Hypothetical protein. | 0.773 |
| dkgA | APA96225.1 | NS506_02156 | NS506_02158 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | KEGG: dpd:Deipe_0121 probable phosphoglycerate mutase. | 0.560 |
| dkgA | APA98789.1 | NS506_02156 | NS506_04743 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Aryl-alcohol dehydrogenase (NADP(+)); Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily; KEGG: bra:BRADO6605 aryl-alcohol dehydrogenase (NADP+). | 0.706 |
| dkgA | APB00029.1 | NS506_02156 | NS506_05992 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Pyridoxine 4-dehydrogenase; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily; KEGG: bur:Bcep18194_B2855 pyridoxine 4-dehydrogenase. | 0.586 |
| dkgA | APB00708.1 | NS506_02156 | NS506_06677 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | KEGG: aav:Aave_4523 superoxide dismutase, Cu-Zn family. | 0.630 |
| dkgA | metH | NS506_02156 | NS506_05146 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.785 |
| dkgA | nasA | NS506_02156 | NS506_00075 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily; Contains 1 4Fe-4S Mo/W bis-MGD-type domain; KEGG: xtn:FD63_02855 assimilatory nitrate reductase catalytic subunit. | 0.568 |
| dkgA | otsB | NS506_02156 | NS506_01225 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | Trehalose-phosphatase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose. Does not hydrolyze maltose, isomaltose, sucrose, cellobiose, p-nitrophenyl-alpha-D- glucopyranoside, and methyl-alpha-D-glucopyranoside. Is also inactive on alpha,beta-trehalose, beta,beta-trehalose, alpha,alpha-trehalose-6,6'-dibehenate, trehalulose, nigerose, and trehalose dimycolate; Belongs to the glycosyl hydrolase 15 family; KEGG: mab:MAB_0578c trehalose 6-phosphate phosphatase. | 0.612 |
| dkgA | ydjG | NS506_02156 | NS506_03491 | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | General stress protein; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily; KEGG: cle:Clole_1539 methylglyoxal reductase; With NAD(+) or NADP(+) as acceptor. | 0.599 |
| metH | dkgA | NS506_05146 | NS506_02156 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selectivity for the substrate and higher thermal stability than 25DKGR-B. Belongs to the aldo/keto reductase family; KEGG: nfa:nfa6720 2,5-diketo-D-gluconate reductase A. | 0.785 |
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