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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nudCNAD(+) diphosphatase; Belongs to the Nudix hydrolase family. NudC subfamily; Contains 1 nudix hydrolase domain; KEGG: ncy:NOCYR_4263 NAD+ diphosphatase. (298 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.923
npdA
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily; Contains 1 deacetylase sirtuin-type domain; KEGG: cai:Caci_7099 NAD-dependent deacetylase; In linear amides.
    
 0.915
qns1
NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.912
nadE
NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
  
 
 0.909
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.909
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); Involved in the catabolism of quinolinic acid (QA); Belongs to the NadC/ModD family; KEGG: nfa:nfa18390 nicotinate-nucleotide pyrophosphorylase (carboxylating).
    
 0.908
APB01006.1
5'-nucleotidase; KEGG: nbr:O3I_017660 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.907
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.906
pncC
Nicotinamide-nucleotide amidase; Belongs to the CinA family; KEGG: ncy:NOCYR_3735 nicotinamide-nucleotide amidase.
    
 0.906
APB01290.1
NAD(P)(+) transhydrogenase (Re/Si-specific); Catalyzes the reversible reductive amination of pyruvate to L-alanine. May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer (By similarity); Belongs to the AlaDH/PNT family; KEGG: nno:NONO_c11750 NAD(P) transhydrogenase subunit alpha; overlaps another CDS with the same product name.
     
  0.900
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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