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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA96348.1Belongs to the cysteine synthase/cystathionine beta- synthase family; KEGG: bra:BRADO3909 cysteine synthase A. (318 aa)    
Predicted Functional Partners:
APA95839.1
Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia (By similarity); Belongs to the trans-sulfuration enzymes family; KEGG: bba:Bd3795 cystathionine gamma-lyase.
 
 0.988
cysE
Serine O-acetyltransferase; Belongs to the transferase hexapeptide repeat family; KEGG: rhb:NY08_3042 serine O-acetyltransferase.
 
 0.985
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.977
APA96927.1
Assimilatory sulfite reductase (ferredoxin); Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family; KEGG: nbr:O3I_009520 sulfite reductase (ferredoxin).
  
 
 0.957
nasA
Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily; Contains 1 4Fe-4S Mo/W bis-MGD-type domain; KEGG: xtn:FD63_02855 assimilatory nitrate reductase catalytic subunit.
  
 
 0.943
APA97114.1
Belongs to the cysteine synthase/cystathionine beta- synthase family; KEGG: scb:SCAB_89801 cysteine synthase A.
  
  
0.928
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.921
cysK
Belongs to the cysteine synthase/cystathionine beta- synthase family; KEGG: rpy:Y013_09270 cysteine synthase A.
  
  
0.920
metY
Transforms O-acetylhomoserine into homocysteine. Belongs to the trans-sulfuration enzymes family; KEGG: cul:CULC22_00509 O-acetylhomoserine (thiol)-lyase.
 
 
 0.903
hydA
Hydrogen dehydrogenase (NADP(+)); Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur- reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family; KEGG: tsi:TSIB_1523 sulfhydrogenase subunit alpha.
     
  0.900
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (40%) [HD]
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