STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA96355.1Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family. (292 aa)    
Predicted Functional Partners:
APB00311.1
HTH-type transcriptional regulator XapR; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.773
APA98564.1
HTH-type transcriptional regulator AlsR; Regulates the expression of the alsSD operon for acetoin biosynthesis. Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.770
APB00487.1
HTH-type transcriptional regulator TsaR; Regulates expression of the tsaMBCD1 operon and of tsaT in response to p-toluenesulfonate (TSA). Acts by binding directly to the promoter region. Binding to the tsa promoter depends on TSA concentration; Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.766
APA99883.1
HTH-type transcriptional regulator PgrR; Regulates the expression of genes involved in peptidoglycan (PG) degradation. Could play a role in switch control between recycling and degradation of PG peptides. Negatively regulates the expression of the ycjY-ymjD-ymjC-mpaA operon by binding to the PgrR-box. In addition, other genes are predicted to be under the control of PgrR, including genes related to membrane formation and function; Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.749
APB01003.1
Transcriptional trans-activator of the gene (mprA) for the small neutral protease. Contains 1 HTH lysR-type DNA-binding domain.
  
     0.747
APB01474.1
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression; Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.740
APA95778.1
HTH-type transcriptional regulator BsdA; Could be a positive regulator of bsdBCD expression in response to salicylic acid; Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.724
APA95018.1
HTH-type transcriptional regulator TrpI; Activates the expression of the trpBA genes, which encode the two tryptophan synthase subunits, and represses initiation at its own promoter. Acts by binding to two adjacent sites in the intergenic region. In the absence of the inducer indoleglycerol phosphate (InGP), TrpI binds to site I. In the presence of InGP, TrpI binds to site I and site II. Binding to site II is site I dependent. InGP strongly stimulates binding to site II and is required for maximal activation of trpBA; Contains 1 HTH lysR-type DNA-binding domain; Belongs to the LysR tra [...]
  
     0.671
APA96356.1
Putative transporter YgaY; Belongs to the major facilitator superfamily.
  
    0.559
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.