| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA94860.1 | APA96392.1 | NS506_00781 | NS506_02326 | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | 0.482 |
| APA94860.1 | APA99997.1 | NS506_00781 | NS506_05961 | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channe; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subuni [...] | 0.513 |
| APA94860.1 | atpD | NS506_00781 | NS506_07196 | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.782 |
| APA94860.1 | glcD | NS506_00781 | NS506_03267 | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | (S)-2-hydroxy-acid oxidase; The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall). Belongs to the oxygen-dependent FAD-linked oxidoreductase family; Contains 1 FAD-binding PCMH-type domain; KEGG: gba:J421_1680 glycolate oxidase. | 0.531 |
| APA96392.1 | APA94860.1 | NS506_02326 | NS506_00781 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | 0.482 |
| APA96392.1 | APA98999.1 | NS506_02326 | NS506_04953 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | Uncharacterized protein; Belongs to the PhyH family. | 0.445 |
| APA96392.1 | APA99997.1 | NS506_02326 | NS506_05961 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channe; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subuni [...] | 0.459 |
| APA96392.1 | APB00696.1 | NS506_02326 | NS506_06665 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity); Belongs to the ETF alpha-subunit/FixB family. | 0.470 |
| APA96392.1 | APB00697.1 | NS506_02326 | NS506_06666 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity); Belongs to the ETF beta-subunit/FixA family. | 0.470 |
| APA96392.1 | APB01749.1 | NS506_02326 | NS506_07730 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | Uncharacterized protein; KEGG: nmr:Nmar_1109 phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase; Acting on the aldehyde or oxo group of donors. | 0.604 |
| APA96392.1 | atpD | NS506_02326 | NS506_07196 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.472 |
| APA96392.1 | ectD | NS506_02326 | NS506_03741 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | Ectoine dioxygenase; Involved in the biosynthesis of ectoine ((S)-2-methyl- 1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) which is a highly soluble organic osmolyte, called compatible solute, use to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine (By similarity); Belongs to the PhyH family. EctD subfamily; KEGG: ncy:NOCYR_3186 ectoine hydroxylase; With 2-oxoglutarate as one donor, and incor [...] | 0.445 |
| APA96392.1 | glcD | NS506_02326 | NS506_03267 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | (S)-2-hydroxy-acid oxidase; The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall). Belongs to the oxygen-dependent FAD-linked oxidoreductase family; Contains 1 FAD-binding PCMH-type domain; KEGG: gba:J421_1680 glycolate oxidase. | 0.730 |
| APA96392.1 | plsB | NS506_02326 | NS506_07819 | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | Belongs to the GPAT/DAPAT family; KEGG: nbr:O3I_003480 glycerol-3-phosphate O-acyltransferase. | 0.512 |
| APA98999.1 | APA96392.1 | NS506_04953 | NS506_02326 | Uncharacterized protein; Belongs to the PhyH family. | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | 0.445 |
| APA98999.1 | glcD | NS506_04953 | NS506_03267 | Uncharacterized protein; Belongs to the PhyH family. | (S)-2-hydroxy-acid oxidase; The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall). Belongs to the oxygen-dependent FAD-linked oxidoreductase family; Contains 1 FAD-binding PCMH-type domain; KEGG: gba:J421_1680 glycolate oxidase. | 0.445 |
| APA99997.1 | APA94860.1 | NS506_05961 | NS506_00781 | F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channe; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subuni [...] | Decaprenyl-phosphate phosphoribosyltransferase; Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5- phosphoribose (DPPR); Belongs to the UbiA prenyltransferase family; KEGG: nfa:nfa1790 decaprenyl-phosphate phosphoribosyltransferase. | 0.513 |
| APA99997.1 | APA96392.1 | NS506_05961 | NS506_02326 | F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channe; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subuni [...] | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | 0.459 |
| APA99997.1 | atpD | NS506_05961 | NS506_07196 | F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Key component of the F(0) channe; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subuni [...] | H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.996 |
| APB00696.1 | APA96392.1 | NS506_06665 | NS506_02326 | The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity); Belongs to the ETF alpha-subunit/FixB family. | Aclacinomycin-N/aclacinomycin-A oxidase; Involved in the modification of the terminal sugar residues in the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group. In the first reaction, it catalyzes the oxidation of the hydroxyl group at carbon C4 of the L-rhodinose terminal sugar moiety of aclacinomycin N (AclN) to a keto group, modifying the sugar to cinerulose A and generating aclacinomycin A (AclA). In the second reaction, it catalyzes the elimination of two hydrogen atoms from cinerulose A, leading to a double bond between carbon atoms C2 and C3 a [...] | 0.470 |
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