node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APA96442.1 | APA96565.1 | NS506_02376 | NS506_02501 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 0.404 |
APA96442.1 | APA98097.1 | NS506_02376 | NS506_04049 | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | Hypothetical protein. | 0.510 |
APA96563.1 | APA96565.1 | NS506_02499 | NS506_02501 | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 0.718 |
APA96563.1 | APA96566.1 | NS506_02499 | NS506_02502 | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | Hypothetical protein. | 0.462 |
APA96563.1 | APA98097.1 | NS506_02499 | NS506_04049 | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | Hypothetical protein. | 0.405 |
APA96565.1 | APA96442.1 | NS506_02501 | NS506_02376 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | 0.404 |
APA96565.1 | APA96563.1 | NS506_02501 | NS506_02499 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | 0.718 |
APA96565.1 | APA96566.1 | NS506_02501 | NS506_02502 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | Hypothetical protein. | 0.737 |
APA96565.1 | APA96567.1 | NS506_02501 | NS506_02503 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | KEGG: cpu:cpfrc_00070 triacylglycerol lipase. | 0.484 |
APA96565.1 | APA98097.1 | NS506_02501 | NS506_04049 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | Hypothetical protein. | 0.405 |
APA96565.1 | APA98831.1 | NS506_02501 | NS506_04785 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | Hypothetical protein. | 0.433 |
APA96565.1 | aba1 | NS506_02501 | NS506_03666 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | Zeaxanthin epoxidase; Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. Belongs to the 3-hydroxybenzoate 6-hydroxylase family; KEGG: tps:THAPSDRAFT_270370 zeaxanthin epoxidase. | 0.445 |
APA96565.1 | nicC | NS506_02501 | NS506_06159 | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 6-hydroxynicotinate 3-monooxygenase; Catalyzes the oxidative decarboxylation of 6- hydroxynicotinic acid to 2,5-dihydroxypyridine. Uses NADH in preference to NADPH as an electron donor; Belongs to the 6-hydroxynicotinate 3-monooxygenase family; KEGG: spe:Spro_2311 6-hydroxynicotinate 3-monooxygenase. | 0.401 |
APA96566.1 | APA96563.1 | NS506_02502 | NS506_02499 | Hypothetical protein. | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | 0.462 |
APA96566.1 | APA96565.1 | NS506_02502 | NS506_02501 | Hypothetical protein. | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 0.737 |
APA96566.1 | APA96567.1 | NS506_02502 | NS506_02503 | Hypothetical protein. | KEGG: cpu:cpfrc_00070 triacylglycerol lipase. | 0.594 |
APA96567.1 | APA96565.1 | NS506_02503 | NS506_02501 | KEGG: cpu:cpfrc_00070 triacylglycerol lipase. | Anhydrotetracycline monooxygenase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family. | 0.484 |
APA96567.1 | APA96566.1 | NS506_02503 | NS506_02502 | KEGG: cpu:cpfrc_00070 triacylglycerol lipase. | Hypothetical protein. | 0.594 |
APA98097.1 | APA96442.1 | NS506_04049 | NS506_02376 | Hypothetical protein. | Dimodular nonribosomal peptide synthase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains; Belongs to the ATP-dependent AMP-binding enzyme family; Contains 2 acyl carrier domains; KEGG: nbr:O3I_034810 enterobactin synthetase component F; Nucleotidyltransferases. | 0.510 |
APA98097.1 | APA96563.1 | NS506_04049 | NS506_02499 | Hypothetical protein. | 3-(3-hydroxy-phenyl)propanoic acid hydroxylase; Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline; Belongs to the PheA/TfdB FAD monooxygenase family; KEGG: fal:FRAAL2565 3-(3-hydroxy-phenyl)propionate hydroxylase. | 0.405 |