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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA96948.1HTH-type transcriptional repressor SmtB; Transcriptional regulator involved in zinc homeostasis. Represses the expression of the smtB-zur operon in the absence of zinc. Could act as the metal sensor that controls the expression of zur in response to zinc availability (By similarity); Contains 1 HTH arsR-type DNA-binding domain. (131 aa)    
Predicted Functional Partners:
APA96947.1
Zinc uptake regulation protein; Global transcriptional regulator involved in zinc homeostasis; Belongs to the Fur family.
  
  
 0.958
APA95235.1
Ribonucleotide monophosphatase; Catalyzes the dephosphorylation of an unusually broad range of substrate including deoxyribo- and ribonucleoside tri-, di-, and monophosphates, as well as polyphosphate and glucose-1-P (Glu1P); Belongs to the HAD-like hydrolase superfamily. NagD family.
   
    0.741
garS
Glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.688
APB00230.1
Transcriptional repressor for the arsADRC operon; Contains 1 HTH arsR-type DNA-binding domain.
  
   
 0.569
APA98962.1
Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)); Contains 1 HTH arsR-type DNA-binding domain.
  
   
 0.547
APA98814.1
Cadmium-exporting ATPase; Involved in heavy metal homeostasis. Probably exports nickel and cobalt ions out of the cell (By similarity); Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily; KEGG: rsa:RSal33209_2182 Cd2+/Zn2+-exporting ATPase.
 
  
 0.414
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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