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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA97150.1Alanine dehydrogenase; May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer; Belongs to the AlaDH/PNT family; KEGG: mag:amb4487 alanine dehydrogenase. (381 aa)    
Predicted Functional Partners:
APB01472.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.946
alaA
Valine--pyruvate transaminase; Involved in the biosynthesis of alanine; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: asd:AS9A_4094 alanine-synthesizing transaminase.
     
 0.906
APA99893.1
Valine--pyruvate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ncy:NOCYR_2246 alanine-synthesizing transaminase.
     
 0.906
pntB
NAD(P)(+) transhydrogenase (Re/Si-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
      0.906
ald
NAD(P)(+) transhydrogenase (Re/Si-specific); May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer; Belongs to the AlaDH/PNT family; KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha.
  
  
 
0.901
tsaE
Alanine racemase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity); Belongs to the TsaE family; KEGG: krh:KRH_06630 alanine racemase; overlaps another CDS with the same product name.
  
  
 0.765
gltB
Glutamate synthase (NADPH); Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules; Belongs to the glutamate synthase family; Contains 1 glutamine amidotransferase type-2 domain; KEGG: nfa:nfa960 glutamate synthase (NADPH/NADH) large chain.
      
 0.618
APA97149.1
Hypothetical protein.
       0.509
APA98756.1
Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operon; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity); Contains 1 HTH asnC-type DNA-binding domain.
     
 0.447
gldC
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.437
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (58%) [HD]
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