| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA96143.1 | APA96145.1 | NS506_02076 | NS506_02078 | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane; Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family. | Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC; nuoA; dcu; dcu; sdhCDA; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity); Contains 1 response regulatory domain. | 0.732 |
| APA96143.1 | APA97451.1 | NS506_02076 | NS506_03399 | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane; Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family. | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | 0.466 |
| APA96145.1 | APA96143.1 | NS506_02078 | NS506_02076 | Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC; nuoA; dcu; dcu; sdhCDA; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity); Contains 1 response regulatory domain. | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane; Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family. | 0.732 |
| APA96145.1 | APA97451.1 | NS506_02078 | NS506_03399 | Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC; nuoA; dcu; dcu; sdhCDA; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity); Contains 1 response regulatory domain. | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | 0.928 |
| APA97448.1 | APA97449.1 | NS506_03396 | NS506_03397 | Hypothetical protein. | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | 0.966 |
| APA97448.1 | APA97450.1 | NS506_03396 | NS506_03398 | Hypothetical protein. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | 0.964 |
| APA97448.1 | APA97451.1 | NS506_03396 | NS506_03399 | Hypothetical protein. | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | 0.587 |
| APA97448.1 | APA97452.1 | NS506_03396 | NS506_03400 | Hypothetical protein. | Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions (By similarity); Contains 1 response regulatory domain. | 0.590 |
| APA97448.1 | APA99217.1 | NS506_03396 | NS506_05171 | Hypothetical protein. | Uncharacterized protein; Contains 1 PAC (PAS-associated C-terminal) domain; Contains 1 PAS (PER-ARNT-SIM) domain; Contains 1 PPM-type phosphatase domain; Contains 1 STAS domain; KEGG: mmc:Mmcs_0350 null; Phosphotransferases with a nitrogenous group as acceptor. | 0.431 |
| APA97449.1 | APA97448.1 | NS506_03397 | NS506_03396 | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | Hypothetical protein. | 0.966 |
| APA97449.1 | APA97450.1 | NS506_03397 | NS506_03398 | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | 0.967 |
| APA97449.1 | APA97451.1 | NS506_03397 | NS506_03399 | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | 0.581 |
| APA97449.1 | APA97452.1 | NS506_03397 | NS506_03400 | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions (By similarity); Contains 1 response regulatory domain. | 0.575 |
| APA97450.1 | APA97448.1 | NS506_03398 | NS506_03396 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | Hypothetical protein. | 0.964 |
| APA97450.1 | APA97449.1 | NS506_03398 | NS506_03397 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain. | 0.967 |
| APA97450.1 | APA97451.1 | NS506_03398 | NS506_03399 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | 0.573 |
| APA97450.1 | APA97452.1 | NS506_03398 | NS506_03400 | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family; Contains 1 ABC transporter domain. | Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox conditions (By similarity); Contains 1 response regulatory domain. | 0.573 |
| APA97451.1 | APA96143.1 | NS506_03399 | NS506_02076 | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane; Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family. | 0.466 |
| APA97451.1 | APA96145.1 | NS506_03399 | NS506_02078 | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC; nuoA; dcu; dcu; sdhCDA; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA (By similarity); Contains 1 response regulatory domain. | 0.928 |
| APA97451.1 | APA97448.1 | NS506_03399 | NS506_03396 | Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: nbr:O3I_016910 two-component system, CitB family, sensor kinase. | Hypothetical protein. | 0.587 |
STRING v12.5 is now available!
