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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA97498.1Histidine kinase; KEGG: sals:SLNWT_5081 two-component system, OmpR family, sensor kinase. (412 aa)    
Predicted Functional Partners:
APA97497.1
Transcriptional regulatory protein; Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin (By similarity); Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain.
 
 
 0.963
APA96511.1
Response regulator ArlR; Member of the two-component regulatory system ArlS/ArlR; Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain.
 
 
 0.851
APA96152.1
Chemotaxis response regulator protein-glutamate methylesterase; Involved in the modulation of the chemotaxis syste; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR; Contains 1 cheB-type methylesterase domain; Contains 1 response regulatory domain.
 
 
 0.849
APA98486.1
Member of the two-component regulatory system GlrR/GlrK that up-regulates transcription of the glmY sRNA when cells enter the stationary growth phase. Regulates glmY transcription by binding to three conserved sites in the purL-glmY intergenic region; Contains 1 response regulatory domain; Contains 1 sigma-54 factor interaction domain.
 
 
 0.849
APB01307.1
Member of the two-component regulatory system PhoP/PhoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase. Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain.
 
 
 0.849
APA94242.1
Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism. Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain.
 
 
 0.848
rcsC
Histidine kinase; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions (By similarity); Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain; KEGG: kmi:VW41_15445 two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC; overlaps another CDS with the same product name.
 
 
 0.848
evgS
Histidine kinase; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals (By similarity); Contains 1 histidine kinase domain; Contains 1 HPt domain; Contains 1 response regulatory domain; KEGG: eco:b2370 two-component system, NarL family, sensor histidine kinase EvgS; overlaps another CDS with the same product name.
 
 
 0.844
APA95408.1
CAI-1 autoinducer sensor kinase/phosphatase CqsS; Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to LuxU and LuxO; Contains 1 histidine kinase domain; Contains 1 response regulatory domain.
 
 
 0.843
APB01310.1
Response regulator ArlR; Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence; Contains 1 OmpR/PhoB-type DNA-binding domain; Contains 1 response regulatory domain.
 
 
 0.843
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (46%) [HD]
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