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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA97659.1Involved in the biosynthesis of tri- and tetraketide alpha-pyrones. Pks18 catalyzes the extension of medium- and long- chain aliphatic acyl-CoA substrates by using malonyl-CoA as an extender molecule to synthesize polyketide products (By similarity); Belongs to the chalcone/stilbene synthases family. (414 aa)    
Predicted Functional Partners:
APA97660.1
Acyl-lipid (7-3)-desaturase, chloroplastic; Fatty acid desaturase that introduces a cis double bond at the 4-position in 16-carbon polyunsaturated fatty acids that contain a Delta(7) double bond, resulting in the production of 16 carbon fatty acid (7Z,10Z,13Z)-hexadeca-7,10,13-trienoate; Belongs to the fatty acid desaturase family; Contains 1 cytochrome b5 heme-binding domain; KEGG: cre:CHLREDRAFT_32523 fatty acid desaturase (delta-4 desaturase); With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water.
 
  
 0.903
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.891
APA98436.1
V-type ATP synthase subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. Belongs to the V-ATPase 116 kDa subunit family.
   
 0.885
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.835
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.820
ntpA
H(+)-transporting two-sector ATPase; Involved in ATP-driven sodium extrusion. Belongs to the ATPase alpha/beta chains family; KEGG: kal:KALB_4145 V/A-type H+-transporting ATPase subunit A.
   
 0.770
APA97658.1
ABC transporter ATP-binding protein; Mediates resistance to the antibacterial peptide microcin J25. Functions as an efflux pump for microcin J25. Requires TolC for export of microcin J25; Belongs to the ABC transporter superfamily; Contains 1 ABC transmembrane type-1 domain; Contains 1 ABC transporter domain.
 
   
 0.761
atpB
V-type proton ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
   
 0.697
gshA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
   
 0.685
APA98434.1
Hypothetical protein.
   
 0.671
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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