Long-chain-fatty-acid--CoA ligase; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: sth:STH3016 long-chain acyl-CoA synthetase.

Bacitracin synthase; Activates five amino acids, incorporates two D-amino acids, releases and cyclizes the mature bacitracin. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 5 acyl carrier domains.

Long-chain-fatty-acid--CoA/3-oxocholest-4-en-26- oate--CoA ligase; Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension. Also involved in the degradation of cholesterol via the degradation of the side chains of C-24 branched-chain sterols. Catalyzes the ATP-dependent CoA thioesterification of the sterol 3-oxocholest-4-en-26-oate to yield 3-oxocholest-4-en-26- oyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: rha:RHA1_ro04675 [...]

Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.

Aspartate racemase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family; Contains 4 acyl carrier domains; KEGG: rha:RHA1_ro06664 aspartate racemase.

Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: pgv:SL003B_1091 acetyl-CoA synthetase.

Long-chain-fatty-acid--AMP ligase FadD32; Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase (PKS) for further chain extension; Belongs to the ATP-dependent AMP-binding enzyme family.

2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase; Catalyzes the activation of 2-hydroxy-7-methoxy-5- methyl-1-naphthoate in the biosynthesis of the naphthoate moiety of the neocarzinostatin chromophore. Also catalyzes the activation of other 1-naphthoic acid analogs such as 2-hydroxy-5-methyl-1- naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate in vitro; Belongs to the ATP-dependent AMP-binding enzyme family.

Bifunctional protein Aas; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the N-terminal sectio; belongs to the 2-acyl-GPE acetyltransferase family; In the C-terminal sectio; belongs to the ATP- dependent AMP-binding enzyme family.