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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edaBelongs to the KHG/KDPG aldolase family; KEGG: msm:MSMEG_3788 2-dehydro-3-deoxyphosphogluconate aldolase. (213 aa)    
Predicted Functional Partners:
kdgK
2-dehydro-3-deoxygluconokinase; May play an important role in maintaining the flux of carbon towards starch formation; Belongs to the carbohydrate kinase PfkB family; KEGG: nbr:O3I_013230 2-dehydro-3-deoxygluconokinase.
 
 
 0.988
aceB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.911
aceA
Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family; KEGG: mab:MAB_4095c isocitrate lyase.
     
 0.910
APB01298.1
(S)-2-hydroxy-acid oxidase; Belongs to the FAD-binding oxidoreductase/transferase type 4 family; Contains 1 FAD-binding PCMH-type domain; KEGG: cct:CC1_16380 glycolate oxidase.
   
 
 0.908
gapA
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family; KEGG: pae:PA3001 glyceraldehyde 3-phosphate dehydrogenase.
  
 
 0.865
gap
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family; KEGG: mtu:Rv1436 glyceraldehyde 3-phosphate dehydrogenase.
  
 
 0.865
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family; KEGG: mva:Mvan_4877 glucose-6-phosphate isomerase.
  
 
 0.859
APA97573.1
Belongs to the pyruvate kinase family; In the C-terminal sectio; belongs to the PEP- utilizing enzyme family; KEGG: cva:CVAR_1215 pyruvate kinase.
    
 0.843
APA99205.1
Belongs to the pyruvate kinase family; KEGG: mva:Mvan_0632 pyruvate kinase.
    
 0.843
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.839
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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