Belongs to the dehydroquinate synthase family; KEGG: ppu:PP_5078 3-dehydroquinate synthase.

Shikimate dehydrogenase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis; In the N-terminal sectio; belongs to the dehydroquinate synthase family; In the 2nd sectio; belongs to the EPSP synthase family; In the 3rd sectio; belongs to the shikimate kinase family; In the 4th sectio; belongs to the type-I 3- dehydroquinase family; In the C-terminal sectio; belongs to the shikimate dehydrogenase family; KEGG: mtu:Rv2552c shikimate dehydrogenase.

3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.

3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).

C7-cyclitol synthase using sedo-heptulose 7-phosphate, but not ido-heptulose 7-phosphate and 3-deoxy-arabino- heptulosonate 7-phosphate, as a substrate. Involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Belongs to the dehydroquinate synthase family; KEGG: mmi:MMAR_0578 3-dehydroquinate synthase.

3-deoxy-7-phosphoheptulonate synthase; Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate; Belongs to the class-II DAHP synthase family; KEGG: mtu:Rv2178c 3-deoxy-7-phosphoheptulonate synthase.

Prephenate dehydrogenase; Catalyzes the NAD(+)-dependent conversion of prephenate to p-hydroxyphenylpyruvate, with the elimination of carbon dioxide. Is a key regulatory enzyme in tyrosine biosynthesis. Displays no chorismate mutase (CM) activity, in contrast to TyrA from E. coli and some other bacteria, that are bifunctional and possess a CM domain; Contains 1 prephenate/arogenate dehydrogenase domain; KEGG: pdx:Psed_0331 prephenate dehydrogenase.