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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98342.13-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: xau:Xaut_1623 3-oxoacyl-(acyl-carrier protein) reductase. (78 aa)    
Predicted Functional Partners:
APA98343.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the second of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3- ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of m [...]
     0.983
APB00300.1
6-methylsalicylic acid synthase; Contains 3 acyl carrier domains; KEGG: fre:Franean1_3611 6-methylsalicylic acid synthase.
 
 
 0.772
APA96452.1
Fatty acid synthase subunit beta; Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. Belongs to the fungal fatty acid synthetase subunit beta family; Contains 1 MaoC-like domain; KEGG: nno:NONO_c62310 fatty acid synthase, bacteria type; Transferring groups other than amino-acyl groups.
  
 0.763
APA97724.1
Glucose 1-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.751
APA96220.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: aau:AAur_0876 meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase; With NAD(+) or NADP(+) as acceptor.
  
     0.747
mabA
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: nfa:nfa34770 beta-ketoacyl ACP reductase.
  
     0.735
APA99437.1
3-oxoacyl-[acyl-carrier-protein] reductase; Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphate, 4-phthalaldehyde, 2-nitrobenzaldehyde, pyridine, formaldehyde, 2-carboxybenzaldehyde or sugars; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: bpe:BP2554 3-oxoacyl-(acyl-carrier protein) reductase.
  
     0.728
APA99892.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: rhi:NGR_c29880 2-keto-3-deoxy-L-fuconate dehydrogenase; With NAD(+) or NADP(+) as acceptor.
  
     0.727
APB00864.1
3(or 17)-beta-hydroxysteroid dehydrogenase; Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: ppuu:PputUW4_01679 3(or 17)beta-hydroxysteroid dehydrogenase.
  
     0.726
APA99977.1
3-oxoacyl-[acyl-carrier-protein] reductase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP- dependent oxidation of L-allo-threonine to L-2-amino-3-keto- butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3- hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L- glycerate; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: cbd:CBUD_0470 3-oxoacyl-(acyl-carrier protein) reductase.
  
     0.725
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (52%) [HD]
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