close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98451.1Putative NAD(P)H nitroreductase acg; Belongs to the nitroreductase family. (333 aa)    
Predicted Functional Partners:
APA98453.1
Hypothetical protein.
  
  
 0.530
APA99746.1
Belongs to the ABC transporter superfamily; Contains 1 ABC transmembrane type-2 domain; Contains 1 ABC transporter domain.
 
  
 0.504
APA98452.1
Alpha,alpha-trehalose phosphorylase; Belongs to the glycosyl hydrolase 65 family; KEGG: stp:Strop_0438 alpha,alpha-trehalose phosphorylase.
       0.500
APA97829.1
Hypothetical protein.
 
  
 0.499
APA94704.1
Hypothetical protein.
 
     0.496
APB00017.1
Hypothetical protein.
  
     0.492
APA97654.1
Hypoxia sensor histidine kinase response regulator DosT; Interacts with the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. May act as a direct hypoxia sensor (rather than a redox sensor; the normal state is the oxygenated form, while the deoxy form is probably active for phosphate transfer. May be the secondary sensor for CO. Donates a phosphate group to DevR (DosR) (By similarity); Contains 2 GAF domains; Contains 1 histidine kinase domain; KEGG: mmc:Mmcs_1077 null; Phosphotransferases with a nitrogenous group as acceptor.
 
     0.466
APA97377.1
Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. Belongs to the arsA ATPase family; KEGG: mbk:K60_022650 arsenite-transporting ATPase.
  
   
 0.459
APA97456.1
Gamma-glutamyltransferase; KEGG: amd:AMED_0106 gamma-glutamyltranspeptidase / glutathione hydrolase.
 
    0.457
APA98380.1
Histidine kinase; Member of the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. May act as a redox sensor (rather than a direct hypoxia sensor; the normal (aerobic growth) state is the Fe(3+) form, while the reduced (anaerobic growth) Fe(2+) form is probably active for phosphate transfer. It is probably reduced by flavin nucleotides such as FMN and FAD. May be the primary sensor for CO. Donates a phosphate group to DevR (DosR) (By similarity); Contains 2 GAF domains; Contains 1 histidine kinase domain; KEGG: mtu:Rv3132c two-component sy [...]
 
     0.456
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.