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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98776.1Ribokinase; Belongs to the carbohydrate kinase PfkB family; KEGG: amd:AMED_9092 ribokinase. (502 aa)    
Predicted Functional Partners:
yihV
Sulfofructose kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
  0.975
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family; KEGG: asd:AS9A_1895 transketolase.
  
 0.931
prpS
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.926
APA96651.1
Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent); This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family; KEGG: nfa:nfa44530 phosphoglucomutase.
   
 0.918
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.912
rpiB
Ribose-5-phosphate isomerase; Belongs to the LacAB/RpiB family; KEGG: nml:Namu_2335 ribose 5-phosphate isomerase B.
  
 
 0.912
APB00956.1
Ribose-5-phosphate isomerase; Belongs to the LacAB/RpiB family; KEGG: mtu:Rv2465c ribose 5-phosphate isomerase B.
  
 
 0.912
pdxS
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing); Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
     
 0.814
pdxT
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
 0.814
iolB
KEGG: nbr:O3I_031800 5-deoxy-glucuronate isomerase.
 
  
 0.683
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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