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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98811.1Ferric uptake regulation protein; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes; Belongs to the Fur family. (163 aa)    
Predicted Functional Partners:
katG
Catalase peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
 
   
 0.909
APB00036.1
Peroxiredoxin; Together with AhpD, DltA and Lpd constitutes an NADH- dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in detoxification of isoniazid (By similarity); Belongs to the AhpC/TSA family; Contains 1 thioredoxin domain; KEGG: mtu:Rv2428 peroxiredoxin (alkyl hydroperoxide reductase subunit C).
  
  
 0.750
katE
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family; KEGG: sals:SLNWT_0316 catalase.
    
 0.733
APA96947.1
Zinc uptake regulation protein; Global transcriptional regulator involved in zinc homeostasis; Belongs to the Fur family.
  
   
 0.689
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.673
gltB
Glutamate synthase (NADPH); Required for the assimilation of symbiotically fixed nitrogen into amino acids in root nodules; Belongs to the glutamate synthase family; Contains 1 glutamine amidotransferase type-2 domain; KEGG: nfa:nfa960 glutamate synthase (NADPH/NADH) large chain.
     
 0.622
APB00015.1
Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess. Contains 1 HTH dtxR-type DNA-binding domain.
  
  
 0.602
APA98123.1
Hypothetical protein.
  
    0.548
APA98296.1
Hypothetical protein.
  
    0.548
APB01320.1
Hypothetical protein.
  
    0.548
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: medium (44%) [HD]
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