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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98838.1Cholesterol oxidase; Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation process. Required for virulence (By similarity); Belongs to the GMC oxidoreductase family. Highly divergent; KEGG: nfa:nfa26130 cholesterol oxidase. (574 aa)    
Predicted Functional Partners:
APA94516.1
Catalyzes the C-27 hydroxylation of cholest-4-en-3-one and cholesterol and subsequently oxidizes the alcohol of the former to the cholest-4-en-3-one-27-oic acid via the aldehyde intermediate. Cyp125 is required to incorporate the cholesterol side-chain carbon atoms into cellular lipids; Belongs to the cytochrome P450 family; KEGG: mkn:MKAN_23385 cholest-4-en-3-one 26-monooxygenase.
     
 0.905
APA95373.1
Catalyzes the C-27 hydroxylation of cholest-4-en-3-one and cholesterol and subsequently oxidizes the alcohol of the former to the cholest-4-en-3-one-27-oic acid via the aldehyde intermediate. Required to incorporate the cholesterol side-chain carbon atoms into cellular lipids; Belongs to the cytochrome P450 family; KEGG: mgi:Mflv_1607 cholest-4-en-3-one 26-monooxygenase.
     
 0.905
APA99411.1
Catalyzes the C-27 hydroxylation of cholest-4-en-3-one and cholesterol and subsequently oxidizes the alcohol of the former to the cholest-4-en-3-one-27-oic acid via the aldehyde intermediate. Required to incorporate the cholesterol side-chain carbon atoms into cellular lipids; Belongs to the cytochrome P450 family; KEGG: rpy:Y013_19380 cholest-4-en-3-one 26-monooxygenase.
     
 0.905
APA98837.1
Hypothetical protein.
 
    0.645
APA94132.1
Hypothetical protein.
    
 0.557
APA94133.1
Hypothetical protein.
    
 0.557
APA94656.1
Hypothetical protein.
    
 0.557
APA95399.1
Uncharacterized protein; To M. tuberculosis Rv1362c; overlaps another CDS with the same product name.
    
 0.557
APA95400.1
Uncharacterized protein; To M. tuberculosis Rv1363c; overlaps another CDS with the same product name.
    
 0.557
APA98471.1
Hypothetical protein.
    
 0.557
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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