STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA98915.1Resuscitation-promoting factor RpfB; Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells; Belongs to the transglycosylase family. Rpf subfamily; Contains 1 G5 domain. (111 aa)    
Predicted Functional Partners:
APA99984.1
Hypothetical protein.
  
   0.759
APA98284.1
Hypothetical protein.
 
     0.548
APA94719.1
Uncharacterized protein; To M. tuberculosis Rv0007.
   
    0.534
APB00165.1
Hypothetical protein.
  
   
 0.496
APB00958.1
Thioredoxin-like reductase; In vitro, the reduced form of Rv2466c catalyzes the reduction and activation of TP053, which is a thienopyrimidine derivative drug that can kill both replicating and non-replicating M. tuberculosis.
  
     0.470
APB00224.1
Hypothetical protein.
   
  
 0.463
APB00832.1
H(+)-stimulated, divalent metal cation uptake system; In the C-terminal sectio; belongs to the NRAMP family.
   
  
 0.463
amiA
N-acetylmuramoyl-L-alanine amidase; Cell-wall hydrolase that hydrolyzes the amide bond between N-acetylmuramic acid and L-alanine in cell-wall glycopeptides. Is able to lyse whole mycobacteria, release peptidoglycan from the cell wall of M. luteus and M. smegmatis, and cleave N-acetylmuramoyl-L-alanyl-D-isoglutamine, releasing free N- acetylmuramic acid and dipeptide; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family; KEGG: nfa:nfa56640 N-acetylmuramoyl-L-alanine amidase.
 
  
 0.447
otsB
Trehalose-phosphatase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose. Does not hydrolyze maltose, isomaltose, sucrose, cellobiose, p-nitrophenyl-alpha-D- glucopyranoside, and methyl-alpha-D-glucopyranoside. Is also inactive on alpha,beta-trehalose, beta,beta-trehalose, alpha,alpha-trehalose-6,6'-dibehenate, trehalulose, nigerose, and trehalose dimycolate; Belongs to the glycosyl hydrolase 15 family; KEGG: mab:MAB_0578c trehalose 6-phosphate phosphatase.
   
  
 0.430
mca
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
     0.415
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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