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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mabA3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: nfa:nfa34770 beta-ketoacyl ACP reductase. (239 aa)    
Predicted Functional Partners:
fabD
[Acyl-carrier-protein] S-malonyltransferase; Belongs to the FabD family; KEGG: mtu:Rv2243 (acyl-carrier-protein) S-malonyltransferase.
 
 
 0.822
fabI
Enoyl-[acyl-carrier-protein] reductase (NADH); Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily; KEGG: mtu:Rv1484 enoyl ACP reductase.
 
  
 0.781
APA96452.1
Fatty acid synthase subunit beta; Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. Belongs to the fungal fatty acid synthetase subunit beta family; Contains 1 MaoC-like domain; KEGG: nno:NONO_c62310 fatty acid synthase, bacteria type; Transferring groups other than amino-acyl groups.
  
 0.763
APB00071.1
Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.758
APB00300.1
6-methylsalicylic acid synthase; Contains 3 acyl carrier domains; KEGG: fre:Franean1_3611 6-methylsalicylic acid synthase.
 
 
 0.744
APA98342.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family; KEGG: xau:Xaut_1623 3-oxoacyl-(acyl-carrier protein) reductase.
  
     0.735
APA97057.1
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family; KEGG: nfa:nfa16170 beta-ketoacyl ACP synthase; Transferring groups other than amino-acyl groups.
 
 
 0.731
APA98635.1
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family; KEGG: asd:AS9A_1223 beta-ketoacyl ACP synthase; Transferring groups other than amino-acyl groups; overlaps another CDS with the same product name.
 
 
 0.701
APB00070.1
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; Belongs to the beta-ketoacyl-ACP synthases family; KEGG: nbr:O3I_001530 beta-ketoacyl ACP synthase; Transferring groups other than amino-acyl groups.
 
 
 0.694
fabH-2
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.675
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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