STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA99109.1Chemotaxis response regulator protein-glutamate methylesterase; Involved in the modulation of the chemotaxis syste; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR; Contains 1 cheB-type methylesterase domain; Contains 1 response regulatory domain. (222 aa)    
Predicted Functional Partners:
APA99110.1
Histidine kinase; Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation; Contains 1 histidine kinase domain; KEGG: bcv:Bcav_0287 two-component system, NarL family, sensor histidine kinase DesK.
 
 
 0.952
APA98911.1
Protein-glutamate O-methyltransferase; KEGG: psl:Psta_1198 two-component system, chemotaxis family, CheB/CheR fusion protein.
 
 
 0.836
APB00386.1
Histidine kinase; Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions, including production of degradative enzymes such as the neutral and alkaline proteases, flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU, and a protein phosphatase that dephosphorylates phospho- DegU; Contains 1 histidine kinase domain; KEGG: ase:ACPL_3817 two-component syste [...]
 
 0.834
APB01428.1
Histidine kinase; KEGG: nal:B005_2463 two-component system, NarL family, sensor histidine kinase DesK.
 
 0.825
APA99060.1
Histidine kinase; Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation; Contains 1 histidine kinase domain; KEGG: sxi:SXIM_35970 two-component system, NarL family, sensor histidine kinase DesK.
 
 0.820
desK
Histidine kinase; Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation; Contains 1 histidine kinase domain; KEGG: gpo:GPOL_c14480 two-component system, NarL family, sensor histidine kinase DesK.
 
 
 0.818
APA95513.1
Histidine kinase; Interacts with the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. May act as a direct hypoxia sensor (rather than a redox sensor; the normal state is the oxygenated form, while the deoxy form is probably active for phosphate transfer. May be the secondary sensor for CO. Donates a phosphate group to DevR (DosR) (By similarity); Contains 2 GAF domains; Contains 1 histidine kinase domain; KEGG: bsu:BSU09320 two-component system, NarL family, sensor kinase.
 
 
 0.817
APB00657.1
Histidine kinase; Probable member of the two-component regulatory system YxjM/YxjL. May activate YxjL by phosphorylation; Contains 1 histidine kinase domain; KEGG: baci:B1NLA3E_10930 two-component system, NarL family, sensor histidine kinase DesK.
 
 
 0.808
degS
Histidine kinase; KEGG: dmi:Desmer_2528 two-component system, NarL family, sensor histidine kinase DegS.
 
 
 0.804
APA96956.1
Histidine kinase; Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation; Contains 1 histidine kinase domain; KEGG: rer:RER_47110 two-component system, NarL family, sensor histidine kinase DesK.
 
 
 0.794
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.