| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APA95954.1 | helY | NS506_01886 | NS506_05076 | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | 0.679 |
| APA99395.1 | arc | NS506_05349 | NS506_05126 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.404 |
| APA99395.1 | helY | NS506_05349 | NS506_05076 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | 0.645 |
| APA99395.1 | pafA | NS506_05349 | NS506_05082 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.531 |
| APA99395.1 | whiB-2 | NS506_05349 | NS506_02070 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Transcriptional regulator WhiB2; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.836 |
| APA99395.1 | whiB-3 | NS506_05349 | NS506_02124 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Transcriptional regulator WhiB1; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.773 |
| APA99395.1 | whiB-4 | NS506_05349 | NS506_02176 | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | Transcriptional regulator WhiB2; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.836 |
| arc | APA99395.1 | NS506_05126 | NS506_05349 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | 0.404 |
| arc | helY | NS506_05126 | NS506_05076 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | 0.629 |
| arc | pafA | NS506_05126 | NS506_05082 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.943 |
| arc | tatC | NS506_05126 | NS506_05077 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.490 |
| cobB | helY | NS506_06354 | NS506_05076 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | 0.612 |
| helY | APA95954.1 | NS506_05076 | NS506_01886 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...] | 0.679 |
| helY | APA99395.1 | NS506_05076 | NS506_05349 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain. | 0.645 |
| helY | arc | NS506_05076 | NS506_05126 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.629 |
| helY | cobB | NS506_05076 | NS506_06354 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.612 |
| helY | pafA | NS506_05076 | NS506_05082 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.657 |
| helY | tatA | NS506_05076 | NS506_05078 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.671 |
| helY | tatC | NS506_05076 | NS506_05077 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.851 |
| helY | whiB-2 | NS506_05076 | NS506_02070 | Putative helicase HelY; Belongs to the helicase family. SKI2 subfamily; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: nno:NONO_c34160 ATP-dependent RNA helicase HelY; Acting on ATP; involved in cellular and subcellular movement. | Transcriptional regulator WhiB2; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.626 |
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