STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA99398.1Adenylate cyclase; Involved in regulation of glutamate metabolism. Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd and Gdh; Contains 1 FHA domain; KEGG: scl:sce7616 adenylate cyclase. (155 aa)    
Predicted Functional Partners:
APA94736.1
Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 4 PASTA domains; Contains 1 protein kinase domain; KEGG: mkn:MKAN_14950 serine/threonine protein kinase, bacterial; overlaps another CDS with the same product name.
 
 
 
 0.992
APA96072.1
2-oxoglutarate decarboxylase; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha- ketoglutarate, KG), leading to the formation of an enamine- thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2- oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which [...]
   
 
 0.985
APA97383.1
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 4 PASTA domains; Contains 1 protein kinase domain; KEGG: mxa:MXAN_3338 serine/threonine protein kinase, bacterial.
 
 
 
 0.973
pknG
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 1 protein kinase domain; KEGG: nfa:nfa53440 serine/threonine-protein kinase PknG.
 
 
 
 0.966
APA96800.1
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 4 PASTA domains; Contains 1 protein kinase domain; KEGG: psim:KR76_11230 serine/threonine protein kinase, bacterial.
 
 
 
 0.961
APA97953.1
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 1 protein kinase domain; KEGG: svl:Strvi_7954 serine/threonine-protein kinase PknG.
   
 
 0.960
gdh2
Glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family; KEGG: nfa:nfa13060 glutamate dehydrogenase.
    
 
 0.952
APA98033.1
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 1 protein kinase domain; KEGG: cga:Celgi_1526 serine/threonine-protein kinase PknG.
 
 
 0.947
APA94737.1
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family; Contains 4 PASTA domains; Contains 1 protein kinase domain; KEGG: ncy:NOCYR_0025 serine/threonine protein kinase, bacterial; overlaps another CDS with the same product name.
 
 
 
 0.937
APA99397.1
Putative HTH-type transcriptional regulator; Contains 1 HTH merR-type DNA-binding domain.
 
    0.911
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
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