STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APA99774.1Belongs to the serine/threonine dehydratase family; KEGG: msa:Mycsm_00810 threonine dehydratase. (430 aa)    
Predicted Functional Partners:
ilvH
Belongs to the acetolactate synthase small subunit family; Contains 1 ACT domain; KEGG: mgi:Mflv_4238 acetolactate synthase I/III small subunit.
  
 
 0.969
ilvB
Acetolactate synthase; Belongs to the TPP enzyme family; KEGG: nfa:nfa42320 acetolactate synthase I/II/III large subunit.
 
 0.957
leuB
3-isopropylmalate dehydrogenase; Performs an essential role in the oxidative function of the citric acid cycle; Belongs to the isocitrate and isopropylmalate dehydrogenases family; KEGG: nbr:O3I_012795 3-isopropylmalate dehydrogenase.
 
 
 0.950
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
0.949
leuB-2
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
 
 
 0.948
poxB
Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family; KEGG: pae:PA2108 pyruvate dehydrogenase (quinone).
 
 0.945
APA95826.1
Belongs to the cysteine synthase/cystathionine beta- synthase family; KEGG: dma:DMR_17120 cysteine synthase A.
 
 
 0.938
APB01096.1
Acetolactate synthase; Catalyzes the decarboxylation of 2-ketoarginine, leading to the formation of 4-guanidinobutyraldehyde; Belongs to the TPP enzyme family; KEGG: vei:Veis_0339 acetolactate synthase I/II/III large subunit.
  
 0.934
trpB
Tryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.933
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.932
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.