STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APB01252.1Enoyl-CoA hydratase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family; KEGG: bju:BJ6T_58800 enoyl-CoA hydratase. (365 aa)    
Predicted Functional Partners:
APB01251.1
Belongs to the 3-hydroxyisobutyrate dehydrogenase family; KEGG: rei:IE4771_PA00122 3-hydroxyisobutyrate dehydrogenase.
 
 0.988
APB01253.1
Putative medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16; Belongs to the acyl-CoA dehydrogenase family; KEGG: mtu:Rv0752c null; With other acceptors.
 
 0.966
gcdH
Glutaryl-CoA dehydrogenase (ETF); Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive; Belongs to the acyl-CoA dehydrogenase family; KEGG: asd:AS9A_3438 glutaryl-CoA dehydrogenase.
 
 0.960
APB01250.1
Enoyl-CoA hydratase; Could possibly oxidize fatty acids using specific components; Belongs to the enoyl-CoA hydratase/isomerase family; KEGG: gbr:Gbro_4172 enoyl-CoA hydratase.
 
 
 
0.958
APA95498.1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, myristoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons. Belongs to the acyl-CoA dehydrogenase family; KEGG: msm:MSMEG_4715 null; With other acceptors.
  
 0.950
APA99406.1
Acyl-CoA oxidase; Oxidizes the CoA-esters of 2-methyl-branched fatty acids; Belongs to the acyl-CoA oxidase family; KEGG: cva:CVAR_2774 acyl-CoA oxidase.
  
 0.948
fadJ
3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate; In the N-terminal sectio; belongs to the enoyl-CoA hydratase/isomerase family; In the C-terminal sectio; belongs to the 3- hydroxyacyl-CoA dehydrogenase family; KEGG: cter:A606_01190 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
 
 0.943
APA95496.1
Methylcrotonoyl-CoA carboxylase; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family; Contains 1 carboxyltransferase domain; KEGG: rcp:RCAP_rcc01512 3-methylcrotonyl-CoA carboxylase beta subunit.
 
 0.938
APA94639.1
Alcohol dehydrogenase; Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA; Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily; KEGG: rba:RB13260 alcohol dehydrogenase.
  
 0.912
mmsA-2
Malonate-semialdehyde dehydrogenase (acetylating); Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid; Belongs to the aldehyde dehydrogenase family; KEGG: psu:Psesu_2114 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase.
 
 
 0.867
Your Current Organism:
Nocardia seriolae
NCBI taxonomy Id: 37332
Other names: ATCC 43993, CCUG 46828, CIP 104778, DSM 44129, IFO 15557, JCM 3360, N. seriolae, NBRC 15557
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.