STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK2Dedicator of cytokinesis 2. (1811 aa)    
Predicted Functional Partners:
RAC1
Rac family small GTPase 1.
   
 0.975
CRK
CRK proto-oncogene, adaptor protein.
    
 0.960
ELMO1
Engulfment and cell motility 1.
    
 0.947
ELMO2
Engulfment and cell motility 2.
    
 0.931
ELMO3
Engulfment and cell motility 3.
    
 0.931
RHOG
Ras homolog family member G.
   
 0.918
RAC3
Rac family small GTPase 3.
   
 0.878
PEBP1
Phosphatidylethanolamine binding protein 1.
 
      0.826
PTK2
Protein tyrosine kinase 2.
   
 0.822
LYN
LYN proto-oncogene, Src family tyrosine kinase.
   
 0.791
Your Current Organism:
Tupaia belangeri
NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.