PIF1 protein (Tupaia belangeri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PIF1

PIF1 5'-to-3' DNA helicase. (555 aa)

Predicted Functional Partners:

PCNA

0.951

BLM

0.941

ENSTBEP00000008816

0.933

ENSTBEP00000015344

0.924

ENSTBEP00000006684

0.918

ENSTBEP00000011064

0.910

RPA1

0.906

POLE

0.902

POLA1

0.894

ASF1A

0.886

Your Current Organism:

Tupaia belangeri

NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	BLM	ENSTBEP00000000502	ENSTBEP00000005799	Anti-silencing function 1A histone chaperone.	BLM RecQ like helicase.	0.863
ASF1A	ENSTBEP00000006684	ENSTBEP00000000502	ENSTBEP00000006684	Anti-silencing function 1A histone chaperone.	annotation not available	0.876
ASF1A	ENSTBEP00000011064	ENSTBEP00000000502	ENSTBEP00000011064	Anti-silencing function 1A histone chaperone.	annotation not available	0.828
ASF1A	ENSTBEP00000015344	ENSTBEP00000000502	ENSTBEP00000015344	Anti-silencing function 1A histone chaperone.	annotation not available	0.419
ASF1A	PCNA	ENSTBEP00000000502	ENSTBEP00000005136	Anti-silencing function 1A histone chaperone.	Proliferating cell nuclear antigen.	0.849
ASF1A	PIF1	ENSTBEP00000000502	ENSTBEP00000001786	Anti-silencing function 1A histone chaperone.	PIF1 5'-to-3' DNA helicase.	0.886
ASF1A	POLA1	ENSTBEP00000000502	ENSTBEP00000007267	Anti-silencing function 1A histone chaperone.	DNA polymerase alpha 1, catalytic subunit.	0.468
ASF1A	POLE	ENSTBEP00000000502	ENSTBEP00000012075	Anti-silencing function 1A histone chaperone.	DNA polymerase epsilon, catalytic subunit.	0.460
BLM	ASF1A	ENSTBEP00000005799	ENSTBEP00000000502	BLM RecQ like helicase.	Anti-silencing function 1A histone chaperone.	0.863
BLM	ENSTBEP00000006684	ENSTBEP00000005799	ENSTBEP00000006684	BLM RecQ like helicase.	annotation not available	0.977
BLM	ENSTBEP00000008816	ENSTBEP00000005799	ENSTBEP00000008816	BLM RecQ like helicase.	annotation not available	0.985
BLM	ENSTBEP00000011064	ENSTBEP00000005799	ENSTBEP00000011064	BLM RecQ like helicase.	annotation not available	0.731
BLM	ENSTBEP00000015344	ENSTBEP00000005799	ENSTBEP00000015344	BLM RecQ like helicase.	annotation not available	0.797
BLM	PCNA	ENSTBEP00000005799	ENSTBEP00000005136	BLM RecQ like helicase.	Proliferating cell nuclear antigen.	0.953
BLM	PIF1	ENSTBEP00000005799	ENSTBEP00000001786	BLM RecQ like helicase.	PIF1 5'-to-3' DNA helicase.	0.941
BLM	POLA1	ENSTBEP00000005799	ENSTBEP00000007267	BLM RecQ like helicase.	DNA polymerase alpha 1, catalytic subunit.	0.930
BLM	POLE	ENSTBEP00000005799	ENSTBEP00000012075	BLM RecQ like helicase.	DNA polymerase epsilon, catalytic subunit.	0.833
BLM	RPA1	ENSTBEP00000005799	ENSTBEP00000002354	BLM RecQ like helicase.	Replication protein A1.	0.997
ENSTBEP00000006684	ASF1A	ENSTBEP00000006684	ENSTBEP00000000502	annotation not available	Anti-silencing function 1A histone chaperone.	0.876
ENSTBEP00000006684	BLM	ENSTBEP00000006684	ENSTBEP00000005799	annotation not available	BLM RecQ like helicase.	0.977