STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L2Signal induced proliferation associated 1 like 2. (1702 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.873
ENSTBEP00000001329
annotation not available
    
 0.741
AFDN
Afadin, adherens junction formation factor.
    
 0.718
RAP2C
RAP2C, member of RAS oncogene family.
    
 0.715
DIRAS2
DIRAS family GTPase 2.
    
 0.705
RIT2
Ras like without CAAX 2.
    
 0.624
ENSTBEP00000014934
annotation not available
    
 0.591
RALB
RAS like proto-oncogene B.
    
 0.576
ENSTBEP00000008773
annotation not available
    
 0.576
RRAS2
RAS related 2.
    
 0.573
Your Current Organism:
Tupaia belangeri
NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.