STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCR3-hydroxy-3-methylglutaryl-CoA reductase. (867 aa)    
Predicted Functional Partners:
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
  
 
 0.990
ENSTBEP00000004345
annotation not available
  
 
 0.988
MVK
Mevalonate kinase.
  
 0.955
INSIG2
Insulin induced gene 2.
   
 
 0.954
MVD
Mevalonate diphosphate decarboxylase.
  
 
 0.945
SQLE
Squalene epoxidase.
   
  
 0.932
CYP51A1
Cytochrome P450 family 51 subfamily A member 1.
  
  
 0.928
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
    
 0.873
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
    
 0.873
COQ6
Coenzyme Q6, monooxygenase.
   
  
 0.872
Your Current Organism:
Tupaia belangeri
NCBI taxonomy Id: 37347
Other names: T. belangeri, Tupaia glis belangeri, common tree shrew, northern tree shrew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.